FOXA2 anticorps (C-Term)

N° du produit ABIN185022

Cet anticorps anti-FOXA2 est un anticorps Chèvre Polyclonal détectant FOXA2 dans WB, ELISA et IHC. Adapté pour Humain et Rat. Ce Primary Antibody a été cité dans 1 publication.

Aperçu rapide pour FOXA2 anticorps (C-Term) (ABIN185022)

Antigène: FOXA2 (Forkhead Box A2 (FOXA2))

Reactivité: Humain, Rat

Hôte: Chèvre

Clonalité: Polyclonal

Conjugué: Cet anticorp FOXA2 est non-conjugé

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Classe de qualité: Verified

Détail du produit anti-FOXA2 anticorps

Épitope: C-Term

Fonction: FOXA2 / HNF3B

Séquence: GVYSRPIMNS S

Specificité: This antibody is expected to recognise both reported isoforms: NP_068556.2, NP_710141.1

Réactivité croisée: Humain, Souris, Rat

Purification: Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.

Immunogène: Peptide with sequence C-GVYSRPIMNSS, from the C Terminus of the protein sequence according to NP_068556.2, NP_710141.1.

Isotype: IgG

Information d'application

Indications d'application:

Immunohistochemistry: In paraffin embedded Human Prostate shows nuclear staining in the secretory cells of the gland. Recommended concentration: 4-8 μg/mL.

Western Blot: Approx 60 kDa band observed in Human Liver and Rat Lung lysates (calculated MW of 48.3 kDa according to Human NP_710141.1 and 48.5 kDa according to Rat NP_036875.1). The observed molecular weight corresponds to earlier findings in literature (

Peptide ELISA: antibody detection limit dilution 1:4000.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Supplied at 0.5 mg/mL in Tris saline, 0.02 % sodium azide, pH 7.3 with 0.5 % bovine serum albumin.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Minimize freezing and thawing.

Stock: -20 °C

Stockage commentaire: Aliquot and store at -20°C, with minimal freeze/thawing. A working aliquot may be refrigerated at 4°C for a few weeks and still remain viable.

Références pour anticorps anti-FOXA2 (ABIN185022)

Nakamura, Moore, Negishi, Sueyoshi: "Nuclear pregnane X receptor cross-talk with FoxA2 to mediate drug-induced regulation of lipid metabolism in fasting mouse liver." dans: The Journal of biological chemistry, Vol. 282, Issue 13, pp. 9768-76, (2007) (PubMed).

Détails sur FOXA2

Antigène: FOXA2 (Forkhead Box A2 (FOXA2))

Autre désignation: FOXA2

Sujet: FOXA2, HNF3B, forkhead box A2, TCF3B, MGC19807, hepatic nuclear factor-3-beta, hepatocyte nuclear factor 3, beta

ID gène: 3170, 15376, 25099

NCBI Accession: NP_068556, NP_710141

Pathways: Dopaminergic Neurogenesis, Regulation of Carbohydrate Metabolic Process