ABCA1 anticorps

N° du produit ABIN187475

L’anticorps Souris Monoclonal anti-ABCA1 a été validé pour WB, IP, IHC (fro) et EIA. Il convient pour détecter ABCA1 dans des échantillons de Humain.

Aperçu rapide pour ABCA1 anticorps (ABIN187475)

Antigène: ABCA1 (ATP-Binding Cassette, Sub-Family A (ABC1), Member 1 (ABCA1))

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp ABCA1 est non-conjugé

Application: Western Blotting (WB), Immunoprecipitation (IP), Immunohistochemistry (Frozen Sections) (IHC (fro)), Enzyme Immunoassay (EIA)

Clone: AB1-G6

Détail du produit anti-ABCA1 anticorps

Specificité: Mutations in the ABCA1 gene (ATP-binding cassette transporter 1) are associated with Tangier disease (TD). TD is an autosomal recessive disorder resulting from an absence of plasma HDL, cholesterol ester depositing in the reticulo-endothelial system and disorders in cellular lipid trafficking. It is expressed on the plasma membrane and the Golgi complex and is regulated by cholesterol flux. Regulation of the cholesterol flux between HDL and macrophages is competitive between ABCA1 and SR-BI. Species Human. Other species not tested.

Immunogène: Peptide corresponding to amino acids 1800-2260.

Isotype: IgG1

Information d'application

Indications d'application: Immunohistochemistry Western blot ELISA Immunoprecipitation The optimal dilution for a specific application should be determined by the researcher.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: 100 µg of antibody at 1 mg/mL in PBS, pH 7.4, with 0.5% sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Détails sur ABCA1

Antigène: ABCA1 (ATP-Binding Cassette, Sub-Family A (ABC1), Member 1 (ABCA1))

Autre désignation: ABCA1

Pathways: Cellular Response to Molecule of Bacterial Origin, cAMP Metabolic Process, Regulation of Lipid Metabolism by PPARalpha, Lipid Metabolism