Clusterin anticorps
Aperçu rapide pour Clusterin anticorps (ABIN187541)
Antigène
Voir toutes Clusterin (CLU) AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
Clone
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Specificité
- Recognizes human clusterin. Species Reactivity: Human. Others not tested.
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Pureté
- 95 % as determined by SDS-PAGE.
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Immunogène
- Purified human clusterin (TRPM-2).
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Isotype
- IgG1
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Indications d'application
- Immunohistochemistry: Frozen sections. Immunoprecipitation Immunocytochemistry Western blot: Use at approximately a 1:2,000 dilution. The optimal dilution for a specific application should be determined by the researcher.
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Restrictions
- For Research Use only
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Format
- Liquid
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Buffer
- 100 µg of liquid purified monoclonal antibody at 1 mg/mL in PBS containing 0.02% sodium azide.
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Stock
- 4 °C
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- Clusterin (CLU)
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Autre désignation
- Apolipoprotein J (Clusterin)
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Sujet
- Clusterin is the first identified extracellular mammalian chaperone and appears to be implicated in such diverse processes as sperm maturation, regulation of complement activation, programmed cell death, tissue remodeling and lipid transport. Increases in clusterin mRNA and protein have been consistently detected in apoptotic cell death paradigms, establishing clusterin gene expression as a prominent marker of apoptotic cell loss. A dual role has been shown for clusterin in that cells can be protected from damage and dead cells can be more easily removed after some types of cellular damage.
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Pathways
- Apoptose, Negative Regulation of intrinsic apoptotic Signaling
Antigène
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