CBS anticorps (N-Term)

N° du produit ABIN1881141

Cet anticorps anti-CBS est un anticorps Lapin Polyclonal détectant CBS dans WB, IF, IHC (p) et FACS. Adapté pour Humain et Souris. Ce Primary Antibody a été cité dans 2+ publications.

Aperçu rapide pour CBS anticorps (N-Term) (ABIN1881141)

Antigène: CBS (Cystathionine-beta-Synthase (CBS))

Reactivité: Humain, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp CBS est non-conjugé

Application: Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Flow Cytometry (FACS)

Clone: RB22961

Détail du produit anti-CBS anticorps

Épitope: AA 104-133, N-Term

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogène: This CBS antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 104-133 amino acids from the N-terminal region of human CBS.

Isotype: Ig Fraction

Information d'application

Indications d'application: IF: 1:10~50. WB: 1:1000. WB: 1:1000. IHC-P: 1:50~100. FC: 1:10~50

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Date de péremption: 6 months

Références pour anticorps anti-CBS (ABIN1881141)

Lee, Feliers, Mariappan, Sataranatarajan, Choudhury, Gorin, Kasinath: "Tadalafil Integrates Nitric Oxide-Hydrogen Sulfide Signaling to Inhibit High Glucose-induced Matrix Protein Synthesis in Podocytes." dans: The Journal of biological chemistry, Vol. 290, Issue 19, pp. 12014-26, (2015) (PubMed).

Lee, Mariappan, Feliers, Cavaglieri, Sataranatarajan, Abboud, Choudhury, Kasinath: "Hydrogen sulfide inhibits high glucose-induced matrix protein synthesis by activating AMP-activated protein kinase in renal epithelial cells." dans: The Journal of biological chemistry, Vol. 287, Issue 7, pp. 4451-61, (2012) (PubMed).

Détails sur CBS

Antigène: CBS (Cystathionine-beta-Synthase (CBS))

Autre désignation: CBS

Sujet: CBS acts as a homotetramer to catalyze the conversion of homocysteine to cystathionine, the first step in the transsulfuration pathway. This protein is allosterically activated by adenosyl-methionine and uses pyridoxal phosphate as a cofactor. Defects in this gene can cause cystathionine beta-synthase deficiency (CBSD), which can lead to homocystinuria.

Poids moléculaire: 60587

NCBI Accession: NP_000062, NP_001171479, NP_001171480

UniProt: P35520