CREB3 anticorps (N-Term)

N° du produit ABIN1881228

Cet anticorps anti-CREB3 est un anticorps Lapin Polyclonal détectant CREB3 dans WB. Adapté pour Humain. Ce Primary Antibody a été cité dans 2+ publications.

Aperçu rapide pour CREB3 anticorps (N-Term) (ABIN1881228)

Antigène: CREB3 (CAMP Responsive Element Binding Protein 3 (CREB3))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp CREB3 est non-conjugé

Application: Western Blotting (WB)

Clone: RB42213

Détail du produit anti-CREB3 anticorps

Épitope: AA 66-94, N-Term

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogène: This CREB3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 66-94 amino acids from the N-terminal region of human CREB3.

Isotype: Ig Fraction

Information d'application

Indications d'application: WB: 1:1000

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Date de péremption: 6 months

Références pour anticorps anti-CREB3 (ABIN1881228)

Kim, Choi, Choi, Kang, Kim, Lee, Lee, Lee, Kim, Jun, Jeong, Yoon: "HDAC3 selectively represses CREB3-mediated transcription and migration of metastatic breast cancer cells." dans: Cellular and molecular life sciences : CMLS, Vol. 67, Issue 20, pp. 3499-510, (2010) (PubMed).

Audas, Li, Liang, Lu: "A novel protein, Luman/CREB3 recruitment factor, inhibits Luman activation of the unfolded protein response." dans: Molecular and cellular biology, Vol. 28, Issue 12, pp. 3952-66, (2008) (PubMed).

Détails sur CREB3

Antigène: CREB3 (CAMP Responsive Element Binding Protein 3 (CREB3))

Autre désignation: CREB3

Sujet: This gene encodes a transcription factor that is a member of the leucine zipper family of DNA binding proteins. This protein binds to the cAMP-response element and regulates cell proliferation. The protein interacts with host cell factor C1, which also associates with the herpes simplex virus (HSV) protein VP16 that induces transcription of HSV immediate-early genes. This protein and VP16 both bind to the same site on host cell factor C1. It is thought that the interaction between this protein and host cell factor C1 plays a role in the establishment of latency during HSV infection. This protein also plays a role in leukocyte migration, tumor suppression, and endoplasmic reticulum stress-associated protein degradation. Additional transcript variants have been identified, but their biological validity has not been determined.

Poids moléculaire: 41379

NCBI Accession: NP_006359

UniProt: O43889

Pathways: Thyroid Hormone Synthesis, Myometrial Relaxation and Contraction, ER-Nucleus Signaling, Maintenance of Protein Location, Unfolded Protein Response