ENPP1 anticorps (N-Term)

N° du produit ABIN1881296

L’anticorps Lapin Polyclonal anti-ENPP1 a été validé pour WB. Il convient pour détecter ENPP1 dans des échantillons de Humain. Il y a 5+ publications disponibles.

Aperçu rapide pour ENPP1 anticorps (N-Term) (ABIN1881296)

Antigène: ENPP1 (Ectonucleotide Pyrophosphatase/phosphodiesterase 1 (ENPP1))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp ENPP1 est non-conjugé

Application: Western Blotting (WB)

Clone: RB41733

Détail du produit anti-ENPP1 anticorps

Épitope: AA 6-34, N-Term

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogène: This ENPP1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 6-34 amino acids from the N-terminal region of human ENPP1.

Isotype: Ig Fraction

Information d'application

Indications d'application: WB: 1:1000

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Date de péremption: 6 months

Références pour anticorps anti-ENPP1 (ABIN1881296)

Ermakov, Rosenbaum, Malkin, Livshits: "Family-based study of association between ENPP1 genetic variants and craniofacial morphology." dans: Annals of human biology, Vol. 37, Issue 6, pp. 754-66, (2010) (PubMed).

Wang, Peng, Qu, Huang: "[Association and meta-analysis of ENPP1 K121Q with type 2 diabetes in Han Chinese.]." dans: Yi chuan = Hereditas / Zhongguo yi chuan xue hui bian ji, Vol. 32, Issue 8, pp. 808-16, (2010) (PubMed).

Cruz, Valladares-Salgado, Garcia-Mena, Ross, Edwards, Angeles-Martinez, Ortega-Camarillo, de la Peña, Burguete-Garcia, Wacher-Rodarte, Ambriz, Rivera, Dartote, Peralta, Parra, Kumate: "Candidate gene association study conditioning on individual ancestry in patients with type 2 diabetes and metabolic syndrome from Mexico City." dans: Diabetes/metabolism research and reviews, Vol. 26, Issue 4, pp. 261-70, (2010) (PubMed).

Moehlecke, Kramer, Leitão, Krahe, Balbosco, Azevedo, Gross, Canani: "[ENPP1 K121Q polymorphism and ischemic heart disease in diabetic patients]." dans: Arquivos brasileiros de cardiologia, Vol. 94, Issue 2, pp. 157-61, 168-73, 159-63, (2010) (PubMed).

Bailey, Xie, Do, Montpetit, Diaz, Mohan, Keavney, Yusuf, Gerstein, Engert, Anand: "Variation at the NFATC2 locus increases the risk of thiazolidinedione-induced edema in the Diabetes REduction Assessment with ramipril and rosiglitazone Medication (DREAM) study." dans: Diabetes Care, Vol. 33, Issue 10, pp. 2250-3, (2010) (PubMed).

Détails sur ENPP1

Antigène: ENPP1 (Ectonucleotide Pyrophosphatase/phosphodiesterase 1 (ENPP1))

Autre désignation: ENPP1

Sujet: This gene is a member of the ecto-nucleotide pyrophosphatase/phosphodiesterase (ENPP) family. The encoded protein is a type II transmembrane glycoprotein comprising two identical disulfide-bonded subunits. This protein has broad specificity and cleaves a variety of substrates, including phosphodiester bonds of nucleotides and nucleotide sugars and pyrophosphate bonds of nucleotides and nucleotide sugars. This protein may function to hydrolyze nucleoside 5' triphosphates to their corresponding monophosphates and may also hydrolyze diadenosine polyphosphates. Mutations in this gene have been associated with 'idiopathic' infantile arterial calcification, ossification of the posterior longitudinal ligament of the spine (OPLL), and insulin resistance.

Poids moléculaire: 104924

NCBI Accession: NP_006199

UniProt: P22413

Pathways: Regulation of Carbohydrate Metabolic Process