Tel:
+49 (0)241 95 163 153
Fax:
+49 (0)241 95 163 155
E-Mail:
orders@anticorps-enligne.fr

TSC1 anticorps (pSer561)

TSC1 Reactivité: Souris DB Hôte: Lapin Polyclonal RB41237 unconjugated
N° du produit ABIN1881915
  • Antigène Voir toutes TSC1 Anticorps
    TSC1 (Tuberous Sclerosis 1 (TSC1))
    Épitope
    • 24
    • 16
    • 16
    • 16
    • 15
    • 15
    • 13
    • 8
    • 8
    • 8
    • 8
    • 8
    • 7
    • 7
    • 7
    • 7
    • 7
    • 7
    • 7
    • 7
    • 7
    • 7
    • 7
    • 7
    • 7
    • 7
    • 6
    • 6
    • 5
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    pSer561
    Reactivité
    • 188
    • 138
    • 53
    • 24
    • 18
    • 2
    • 1
    • 1
    Souris
    Hôte
    • 301
    • 16
    • 1
    • 1
    Lapin
    Clonalité
    • 303
    • 16
    Polyclonal
    Conjugué
    • 113
    • 37
    • 36
    • 36
    • 32
    • 32
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    Cet anticorp TSC1 est non-conjugé
    Application
    • 230
    • 207
    • 92
    • 28
    • 26
    • 26
    • 16
    • 14
    • 9
    • 7
    • 6
    • 4
    • 3
    • 1
    Dot Blot (DB)
    Purification
    This antibody is purified through a protein A column, followed by peptide affinity purification.
    Immunogène
    This mouse TSC1 Antibody is generated from rabbits immunized with a KLH conjugated synthetic phosphopeptide corresponding to amino acid residues surrounding S561 of mouse TSC1.
    Clone
    RB41237
    Isotype
    Ig Fraction
    Top Product
    Discover our top product TSC1 Anticorps primaire
  • Indications d'application
    DB: 1:500
    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Stock
    4 °C,-20 °C
    Date de péremption
    6 months
  • Akpa, Oyejola: "Modeling the transmission dynamics of HIV/AIDS epidemics: an introduction and a review." dans: Journal of infection in developing countries, Vol. 4, Issue 10, pp. 597-608, (2010) (PubMed).

    Kladney, Cardiff, Kwiatkowski, Chiang, Weber, Arbeit, Lu: "Tuberous sclerosis complex 1: an epithelial tumor suppressor essential to prevent spontaneous prostate cancer in aged mice." dans: Cancer research, Vol. 70, Issue 21, pp. 8937-47, (2010) (PubMed).

  • Antigène
    TSC1 (Tuberous Sclerosis 1 (TSC1))
    Autre désignation
    TSC1 (TSC1 Produits)
    Synonymes
    anticorps LAM, anticorps TSC, anticorps hamartin, anticorps mKIAA0243, anticorps tsc1, anticorps wu:fc38b04, anticorps fa99f04, anticorps wu:fa99f04, anticorps zgc:63657, anticorps TSC complex subunit 1, anticorps tuberous sclerosis 1, anticorps TSC complex subunit 1b, anticorps TSC complex subunit 1a, anticorps TSC1, anticorps Tsc1, anticorps tsc1b, anticorps tsc1, anticorps tsc1a
    Sujet
    In complex with TSC2, inhibits the nutrient-mediated or growth factor-stimulated phosphorylation of S6K1 and EIF4EBP1 by negatively regulating mTORC1 signaling (By similarity). Implicated as a tumor suppressor. Involved in microtubule-mediated protein transport, but this seems to be due to unregulated mTOR signaling (By similarity).
    Poids moléculaire
    128746
    NCBI Accession
    NP_075025
    UniProt
    Q9EP53
    Pathways
    Signalisation RTK, AMPK Signaling, Regulation of Cell Size, Tube Formation
Vous êtes ici:
Support technique