Tuberin anticorps (pSer1365)
Aperçu rapide pour Tuberin anticorps (pSer1365) (ABIN1881940)
Antigène
Voir toutes Tuberin (TSC2) AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
Clone
-
-
Épitope
- pSer1365
-
Homologie
- Rat
-
Purification
- This antibody is purified through a protein A column, followed by peptide affinity purification.
-
Immunogène
- This mouse TSC2 Antibody is generated from rabbits immunized with a KLH conjugated synthetic phosphopeptide corresponding to amino acid residues surrounding S1365 of mouse TSC2.
-
Isotype
- Ig Fraction
-
-
anti-Tuberous Sclerosis 2 (TSC2) (AA 1776-1805) antibody
TSC2 Reactivité: Humain WB, IF, IHC (p) Hôte: Lapin Polyclonal RB13393 unconjugated
anti-Tuberous Sclerosis 2 (TSC2) (AA 1611-1807) antibodyTSC2 Reactivité: Humain, Souris, Rat WB, IHC Hôte: Lapin Polyclonal unconjugated
anti-Tuberous Sclerosis 2 (TSC2) (AA 1601-1750) antibodyTSC2 Reactivité: Humain, Souris, Rat ELISA, IF (cc), IF (p), IHC (p), IHC (fro) Hôte: Lapin Polyclonal unconjugated
anti-Tuberous Sclerosis 2 (TSC2) antibodyKD Validated TSC2 Reactivité: Humain WB, FACS Hôte: Lapin Monoclonal 23GB1120 unconjugated Recombinant Antibody
anti-Tuberous Sclerosis 2 (TSC2) antibodyKD Validated TSC2 Reactivité: Humain WB, FACS Hôte: Lapin Monoclonal 23GB1000 unconjugated Recombinant Antibody
anti-Tuberous Sclerosis 2 (TSC2) (AA 1776-1805) antibodyTSC2 Reactivité: Humain ELISA, WB, IHC, IF Hôte: Lapin Polyclonal unconjugated
anti-Tuberous Sclerosis 2 (TSC2) (pThr1462) antibodyTSC2 Reactivité: Humain, Souris, Rat ELISA, WB, IHC, IF, ICC Hôte: Lapin Polyclonal unconjugated
anti-Tuberous Sclerosis 2 (TSC2) (AA 900-1150) antibodyTSC2 Reactivité: Humain WB, IHC, IF Hôte: Lapin Polyclonal unconjugated
anti-Tuberous Sclerosis 2 (TSC2) (AA 1397-1426) antibodyTSC2 Reactivité: Humain WB, IHC (p) Hôte: Lapin Polyclonal RB42388 unconjugated
anti-Tuberous Sclerosis 2 (TSC2) (pSer1387) antibodyTSC2 Reactivité: Humain DB, IF Hôte: Lapin Polyclonal RB11388 unconjugated
-
-
Indications d'application
- DB: 1:500
-
Restrictions
- For Research Use only
-
-
-
Format
- Liquid
-
Buffer
- Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
-
Agent conservateur
- Sodium azide
-
Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
Stock
- 4 °C,-20 °C
-
Date de péremption
- 6 months
-
-
- Tuberin (TSC2) (Tuberous Sclerosis 2 (TSC2))
-
Autre désignation
- TSC2
-
Sujet
- In complex with TSC1, inhibits the nutrient-mediated or growth factor-stimulated phosphorylation of S6K1 and EIF4EBP1 by negatively regulating mTORC1 signaling. Acts as a GTPase-activating protein (GAP) for the small GTPase RHEB, a direct activator of the protein kinase activity of mTORC1. Implicated as a tumor suppressor. Involved in microtubule-mediated protein transport, but this seems to be due to unregulated mTOR signaling (By similarity). Specifically stimulates the intrinsic GTPase activity of the Ras-related protein RAP1A and RAB5. Suggesting a possible mechanism for its role in regulating cellular growth (By similarity).
-
Poids moléculaire
- 202071
-
UniProt
- Q61037
-
Pathways
- Signalisation RTK, AMPK Signaling, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Regulation of Cell Size, Tube Formation, Protein targeting to Nucleus
Antigène
-
