Filamin A anticorps (AA 1-360)

N° du produit ABIN1882243

Cet anticorps Souris Monoclonal détecte spécifiquement Filamin A dans WB. Il présente une réactivité avec des échantillons de Humain, Souris et Rat. Il a été cité dans 5+ publications.

Aperçu rapide pour Filamin A anticorps (AA 1-360) (ABIN1882243)

Antigène: Filamin A (FLNA) (Filamin A, alpha (FLNA))

Reactivité: Humain, Souris, Rat

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp Filamin A est non-conjugé

Application: Western Blotting (WB)

Clone: 1273CT424-104-153

Détail du produit anti-Filamin A anticorps

Épitope: AA 1-360

Purification: This antibody is purified through a protein G column, followed by dialysis against PBS.

Immunogène: Purified His-tagged FLNA protein was used to produced this monoclonal antibody.

Isotype: IgG1

Information d'application

Indications d'application: WB: 1:1000

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Purified monoclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Date de péremption: 6 months

Références pour anticorps anti-Filamin A (ABIN1882243)

Campos, Rodriguez, Machado Leopoldino, Hait, Lopez Bergami, Castro, Sanchez, Maceyka, Spiegel, Alvarez: "Filamin A Expression Negatively Regulates Sphingosine-1-Phosphate-Induced NF-?B Activation in Melanoma Cells by Inhibition of Akt Signaling." dans: Molecular and cellular biology, (2015) (PubMed).

Li, Liu, Wang, Liu, Liu, Li, Wan, Wang, Zhang, Jin, Liu, Zhu, Liu: "Systematic mapping and functional analysis of a family of human epididymal secretory sperm-located proteins." dans: Molecular & cellular proteomics : MCP, Vol. 9, Issue 11, pp. 2517-28, (2010) (PubMed).

Chen, Zollo, Mazzarella, Ciccodicola, Chen, Zuo, Heiner, Burough, Repetto, Schlessinger, DUrso: "Long-range sequence analysis in Xq28: thirteen known and six candidate genes in 219.4 kb of high GC DNA between the RCP/GCP and G6PD loci." dans: Human molecular genetics, Vol. 5, Issue 5, pp. 659-68, (1997) (PubMed).

Patrosso, Repetto, Villa, Milanesi, Frattini, Faranda, Mancini, Maestrini, Toniolo, Vezzoni: "The exon-intron organization of the human X-linked gene (FLN1) encoding actin-binding protein 280." dans: Genomics, Vol. 21, Issue 1, pp. 71-6, (1994) (PubMed).

Gorlin, Yamin, Egan, Stewart, Stossel, Kwiatkowski, Hartwig: "Human endothelial actin-binding protein (ABP-280, nonmuscle filamin): a molecular leaf spring." dans: The Journal of cell biology, Vol. 111, Issue 3, pp. 1089-105, (1990) (PubMed).

Détails sur Filamin A

Antigène: Filamin A (FLNA) (Filamin A, alpha (FLNA))

Autre désignation: FLNA

Sujet: Promotes orthogonal branching of actin filaments and links actin filaments to membrane glycoproteins. Anchors various transmembrane proteins to the actin cytoskeleton and serves as a scaffold for a wide range of cytoplasmic signaling proteins. Interaction with FLNA may allow neuroblast migration from the ventricular zone into the cortical plate. Tethers cell surface-localized furin, modulates its rate of internalization and directs its intracellular trafficking (By similarity). Involved in ciliogenesis.

Poids moléculaire: 280739

NCBI Accession: NP_001104026, NP_001447

UniProt: P21333

Pathways: TCR Signaling, Maintenance of Protein Location