PCNA anticorps (C-Term)

N° du produit ABIN1882273

Détail du produit anti-PCNA anticorps

Antigène: PCNA (Proliferating Cell Nuclear Antigen (PCNA))

Épitope: AA 236-261, C-Term

Reactivité: Humain, Souris, Rat

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp PCNA est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Homologie: B, Ha, Pr

Purification: This antibody is purified through a protein G column, followed by dialysis against PBS.

Immunogène: This PCNA antibody is generated from mice immunized with a KLH conjugated synthetic peptide between 236-261 amino acids from the C-terminal region of human PCNA.

Clone: 1157CT1-1-3

Isotype: IgG1

Information d'application

Indications d'application: WB: 1:2000. IHC: 1:2000. IHC-P: 1:25. IHC-P: 1:25

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Purified monoclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Date de péremption: 6 months

Références pour anticorps anti-PCNA (ABIN1882273)

Deloukas, Matthews, Ashurst, Burton, Gilbert, Jones, Stavrides, Almeida, Babbage, Bagguley, Bailey, Barlow, Bates, Beard, Beare, Beasley, Bird, Blakey, Bridgeman, Brown, Buck, Burrill, Butler, Carder et al.: "The DNA sequence and comparative analysis of human chromosome 20. ..." dans: Nature, Vol. 414, Issue 6866, pp. 865-71, (2002) (PubMed).

Détails sur PCNA

Antigène: PCNA (Proliferating Cell Nuclear Antigen (PCNA))

Autre désignation: PCNA (PCNA Produits)

Synonymes: anticorps PCNAR, anticorps Pcna/cyclin, anticorps pcna, anticorps AO090003000846, anticorps 53/13, anticorps CG9193, anticorps DmPCNA, anticorps Dmel\\CG9193, anticorps MUS209, anticorps Mus209, anticorps PCNA, anticorps PCNA/mus209, anticorps Pcna, anticorps dPCNA, anticorps l(2)02448, anticorps l(2)56F, anticorps l(2)56Fa, anticorps l(2)s1534, anticorps cb16, anticorps fb36g03, anticorps wu:fa28e03, anticorps wu:fb36g03, anticorps pcna-A, anticorps proliferating cell nuclear antigen, anticorps DNA polymerase III sliding clamp, anticorps Proliferating cell nuclear antigen, anticorps Proliferating cell nuclear antigen-like, anticorps proliferating cell nuclear antigen L homeolog, anticorps proliferating cell nuclear antigen 1, anticorps PCNA, anticorps Pcna, anticorps pcna, anticorps MMP_RS08810, anticorps ANI_1_512014, anticorps AOR_1_1500154, anticorps MGC53867, anticorps pcna.L, anticorps pcna1, anticorps LOC106420145, anticorps pcn1

Sujet: This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand. Induces a robust stimulatory effect on the 3'-5' exonuclease and 3'-phosphodiesterase, but not apurinic-apyrimidinic (AP) endonuclease, APEX2 activities. Has to be loaded onto DNA in order to be able to stimulate APEX2.

Poids moléculaire: 28769

NCBI Accession: NP_002583, NP_872590

UniProt: P12004

Pathways: Telomere Maintenance, Réparation de l'ADN, Mitotic G1-G1/S Phases, DNA Replication, Synthesis of DNA, Autophagy