PITRM1
Reactivité: Humain, Rat, Souris
WB, IHC, ELISA
Hôte: Lapin
Polyclonal
unconjugated
Indications d'application
Suggested dilutions: Western blotting: 1.500-1.3000 Immunohistochemistry: 1.50-1.500
Restrictions
For Research Use only
Format
Liquid
Buffer
0.1 M Tris-buffered saline with 10 % Glycerol (pH 7.0).0.01 % Thimerosal was added as a preservative.
Agent conservateur
Thimerosal (Merthiolate)
Précaution d'utilisation
Biohazard Informations: This product contains thimerosal which is hazardous.
Stock
4 °C/-20 °C
Stockage commentaire
Store at -20 °C for long term preservation (recommended). Store at 4 °C for short term use.
Antigène
PITRM1
(Pitrilysin Metallopeptidase 1 (PITRM1))
Autre désignation
MP1
Sujet
This gene encodes a scaffold protein that functions in the extracellular signal-regulated kinase (ERK) cascade.The protein is localized to late endosomes by the mitogen-activated protein-binding protein-interacting protein, and binds specifically to MAP kinase kinase MAP2K1/MEK1, MAP kinase MAPK3/ERK1, and MAP kinase MAPK1/ERK2.Studies of the orthologous gene in mouse indicate that it regulates late endosomal traffic and cell proliferation.Multiple transcript variants are expressed by this gene, but only one variant is thought to express a protein.[provided by RefSeq]