NK2 Homeobox 5 anticorps (AA 1-188)

N° du produit ABIN1885739

L’anticorps anti-NK2 Homeobox 5 Polyclonal Lapin est utilisé pour la détection de NK2 Homeobox 5 dans des échantillons de Humain. Il a été validé pour WB et IF.

Aperçu rapide pour NK2 Homeobox 5 anticorps (AA 1-188) (ABIN1885739)

Antigène: NK2 Homeobox 5 (NKX2-5)

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp NK2 Homeobox 5 est non-conjugé

Application: Western Blotting (WB), Immunofluorescence (IF)

Détail du produit anti-NK2 Homeobox 5 anticorps

Épitope: AA 1-188

Purification: Purified by antigen-affinity chromatography.

Immunogène: Recombinant protein fragment contain a sequence corresponding to a region within amino acids 1 and 188 of NKX2-5

Information d'application

Indications d'application: Suggested dilutions:
Western blotting: 1.500-1.3000
Immunofluorescence: 1.100-1.200

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: 0.1 M Tris-buffered saline with 10 % Glycerol (pH 7.0).0.01 % Thimerosal was added as a preservative.

Agent conservateur: Thimerosal (Merthiolate)

Précaution d'utilisation: Biohazard Informations: This product contains thimerosal which is hazardous.

Stock: 4 °C/-20 °C

Stockage commentaire: Store at -20 °C for long term preservation (recommended). Store at 4 °C for short term use.

Détails sur NK2 Homeobox 5

Antigène: NK2 Homeobox 5 (NKX2-5)

Autre désignation: NKX2-5

Sujet: Homeobox-containing genes play critical roles in regulating tissue-specific gene expression essential for tissue differentiation, as well as determining the temporal and spatial patterns of development (Shiojima et al., 1995 [PubMed 7665173]).It has been demonstrated that a Drosophila homeobox-containing gene called 'tinman' is expressed in the developing dorsal vessel and in the equivalent of the vertebrate heart.Mutations in tinman result in loss of heart formation in the embryo, suggesting that tinman is essential for Drosophila heart formation.Furthermore, abundant expression of Csx, the presumptive mouse homolog of tinman, is observed only in the heart from the time of cardiac differentiation.CSX, the human homolog of murine Csx, has a homeodomain sequence identical to that of Csx and is expressed only in the heart, again suggesting that CSX plays an important role in human heart formation.[supplied by OMIM]
Synonyms: CSX, CSX1, NKX2.5, NKX2E, NKX4-1

Poids moléculaire: 35 kDa

ID gène: 1482

NCBI Accession: NM_004387, NP_004378

Pathways: Regulation of Muscle Cell Differentiation, Skeletal Muscle Fiber Development