PKLR anticorps (AA 1-230)

N° du produit ABIN1885816

Cet anticorps Lapin Polyclonal détecte spécifiquement PKLR dans WB, IHC et IF. Il présente une réactivité envers Humain.

Aperçu rapide pour PKLR anticorps (AA 1-230) (ABIN1885816)

Antigène: PKLR (Pyruvate Kinase, Liver and RBC (PKLR))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp PKLR est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)

Détail du produit anti-PKLR anticorps

Épitope: AA 1-230

Purification: Purified by antigen-affinity chromatography.

Immunogène: Recombinant protein fragment contain a sequence corresponding to a region within amino acids 1 and 230 of Pyruvate Kinase(liver/RBC)

Information d'application

Indications d'application: Suggested dilutions:
Western blotting: 1.500-1.3000
Immunohistochemistry: 1.50-1.500
Immunofluorescence: 1.100-1.200

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: 0.1 M Tris-buffered saline with 10 % Glycerol (pH 7.0).0.01 % Thimerosal was added as a preservative.

Agent conservateur: Thimerosal (Merthiolate)

Précaution d'utilisation: Biohazard Informations: This product contains thimerosal which is hazardous.

Stock: 4 °C/-20 °C

Stockage commentaire: Store at -20 °C for long term preservation (recommended). Store at 4 °C for short term use.

Détails sur PKLR

Antigène: PKLR (Pyruvate Kinase, Liver and RBC (PKLR))

Sujet: The protein encoded by this gene is a pyruvate kinase that catalyzes the transphosphorylation of phohsphoenolpyruvate into pyruvate and ATP, which is the rate-limiting step of glycolysis.Defects in this enzyme, due to gene mutations or genetic variations, are the common cause of chronic hereditary nonspherocytic hemolytic anemia (CNSHA or HNSHA).Multiple transcript variants encoding different isoforms have been found for this gene.[provided by RefSeq]

Poids moléculaire: 62 kDa

ID gène: 5313

NCBI Accession: NM_000298, NP_000289

Pathways: Ribonucleoside Biosynthetic Process