C5 anticorps (AA 1223-1421)

N° du produit ABIN1885991

L’anticorps Lapin Polyclonal anti-C5 a été validé pour WB et IHC. Il convient pour détecter C5 dans des échantillons de Humain.

Aperçu rapide pour C5 anticorps (AA 1223-1421) (ABIN1885991)

Antigène: C5 (Complement Component 5 (C5))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp C5 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Détail du produit anti-C5 anticorps

Épitope: AA 1223-1421

Purification: Purified by antigen-affinity chromatography.

Immunogène: Recombinant protein fragment contain a sequence corresponding to a region within amino acids 1223 and 1421 of Human C5

Information d'application

Indications d'application: Suggested dilutions:
Western blotting: 1.500-1.3000
Immunohistochemistry: 1.50-1.500

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: 0.1 M Tris-buffered saline with 10 % Glycerol (pH 7.0).0.01 % Thimerosal was added as a preservative.

Agent conservateur: Thimerosal (Merthiolate)

Précaution d'utilisation: Biohazard Informations: This product contains thimerosal which is hazardous.

Stock: 4 °C/-20 °C

Stockage commentaire: Store at -20 °C for long term preservation (recommended). Store at 4 °C for short term use.

Détails sur C5

Antigène: C5 (Complement Component 5 (C5))

Sujet: The protein encoded by this gene is the fifth component of complement, which plays an important role in inflammatory and cell killing processes.This protein is comprised of alpha and beta polypeptide chains that are linked by a disulfide bridge.An activation peptide, C5a, which is an anaphylatoxin that possesses potent spasmogenic and chemotactic activity, is derived from the alpha polypeptide via cleavage with a convertase.The C5b macromolecular cleavage product can form a complex with the C6 complement component, and this complex is the basis for formation of the membrane attack complex, which includes additional complement components.Mutations in this gene cause complement component 5 deficiency, a disease where patients show a propensity for severe recurrent infections.Defects in this gene have also been linked to a susceptibility to liver fibrosis and to rheumatoid arthritis.[provided by RefSeq]

Poids moléculaire: 188 kDa

ID gène: 727

NCBI Accession: NM_001735, NP_001726

Pathways: Système du Complément, Carbohydrate Homeostasis