desert Hedgehog anticorps (AA 135-388)

N° du produit ABIN1886020

Cet anticorps Lapin Polyclonal détecte spécifiquement desert Hedgehog dans WB. Il présente une réactivité envers Humain.

Aperçu rapide pour desert Hedgehog anticorps (AA 135-388) (ABIN1886020)

Antigène: desert Hedgehog (DHH) (Desert Hedgehog (DHH))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp desert Hedgehog est non-conjugé

Application: Western Blotting (WB)

Détail du produit anti-desert Hedgehog anticorps

Épitope: AA 135-388

Purification: Purified by antigen-affinity chromatography.

Immunogène: Recombinant protein fragment contain a sequence corresponding to a region within amino acids 135 and 388 of Dhh

Information d'application

Indications d'application: Suggested dilutions:
Western blotting: 1.500-1.3000

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: 0.1 M Tris-buffered saline with 20 % Glycerol (pH 7.0).0.01 % Thimerosal was added as a preservative.

Agent conservateur: Thimerosal (Merthiolate)

Précaution d'utilisation: Biohazard Informations: This product contains thimerosal which is hazardous.

Stock: 4 °C/-20 °C

Stockage commentaire: Store at -20 °C for long term preservation (recommended). Store at 4 °C for short term use.

Détails sur desert Hedgehog

Antigène: desert Hedgehog (DHH) (Desert Hedgehog (DHH))

Autre désignation: Dhh

Classe de substances: Species

Sujet: This gene encodes a member of the Hedgehog family.The hedgehog gene family encodes signaling molecules that play an important role in regulating morphogenesis.This protein is predicted to be made as a precursor that is autocatalytically cleaved, the N-terminal portion is soluble and contains the signalling activity while the C-terminal portion is involved in precursor processing.More importantly, the C-terminal product covalently attaches a cholesterol moiety to the N-terminal product, restricting the N-terminal product to the cell surface and preventing it from freely diffusing throughout the organism.Defects in this protein have been associated with partial gonadal dysgenesis (PGD) accompanied by minifascicular polyneuropathy.This protein may be involved in both male gonadal differentiation and perineurial development.[provided by RefSeq]

Poids moléculaire: 44 kDa

ID gène: 50846

NCBI Accession: NM_021044, NP_066382

Pathways: Signalisation Hedgehog