SART1 anticorps (AA 137-417)

N° du produit ABIN1886023

Cet anticorps Lapin Polyclonal détecte spécifiquement SART1 dans WB, IF et IHC. Il présente une réactivité envers Humain.

Aperçu rapide pour SART1 anticorps (AA 137-417) (ABIN1886023)

Antigène: SART1 (Squamous Cell Carcinoma Antigen Recognized By T Cells (SART1))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp SART1 est non-conjugé

Application: Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (IHC)

Détail du produit anti-SART1 anticorps

Épitope: AA 137-417

Purification: Purified by antigen-affinity chromatography.

Immunogène: Recombinant protein fragment contain a sequence corresponding to a region within amino acids 137 and 417 of SART1

Information d'application

Indications d'application: Suggested dilutions:
Western blotting: 1.500-1.3000
Immunohistochemistry: 1.100-1.500
Immunofluorescence: 1.100-1.200

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: 0.1 M Tris-buffered saline with 10 % Glycerol (pH 7.0).0.01 % Thimerosal was added as a preservative.

Agent conservateur: Thimerosal (Merthiolate)

Précaution d'utilisation: Biohazard Informations: This product contains thimerosal which is hazardous.

Stock: 4 °C/-20 °C

Stockage commentaire: Store at -20 °C for long term preservation (recommended). Store at 4 °C for short term use.

Détails sur SART1

Antigène: SART1 (Squamous Cell Carcinoma Antigen Recognized By T Cells (SART1))

Autre désignation: SART1

Sujet: This gene encodes two proteins, the SART1(800) protein expressed in the nucleus of the majority of proliferating cells, and the SART1(259) protein expressed in the cytosol of epithelial cancers.The SART1(259) protein is translated by the mechanism of -1 frameshifting during posttranscriptional regulation, its full-length sequence is not published yet.The two encoded proteins are thought to be involved in the regulation of proliferation.Both proteins have tumor-rejection antigens.The SART1(259) protein possesses tumor epitopes capable of inducing HLA-A2402-restricted cytotoxic T lymphocytes in cancer patients.This SART1(259) antigen may be useful in specific immunotherapy for cancer patients and may serve as a paradigmatic tool for the diagnosis and treatment of patients with atopy.The SART1(259) protein is found to be essential for the recruitment of the tri-snRNP to the pre-spliceosome in the spliceosome assembly pathway.[provided by RefSeq]

Poids moléculaire: 90 kDa

ID gène: 9092

NCBI Accession: NM_005146, NP_005137

Pathways: Ribonucleoprotein Complex Subunit Organization