FGFRL1 anticorps (AA 150-486)

N° du produit ABIN1886062

Cet anticorps Lapin Polyclonal détecte spécifiquement FGFRL1 dans WB et IHC. Il présente une réactivité envers Humain.

Aperçu rapide pour FGFRL1 anticorps (AA 150-486) (ABIN1886062)

Antigène: FGFRL1 (Fibroblast Growth Factor Receptor-Like 1 (FGFRL1))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp FGFRL1 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Détail du produit anti-FGFRL1 anticorps

Épitope: AA 150-486

Purification: Purified by antigen-affinity chromatography.

Immunogène: Recombinant protein fragment contain a sequence corresponding to a region within amino acids 150 and 486 of Human FGFRL1

Information d'application

Indications d'application: Suggested dilutions:
Western blotting: 1.500-1.3000
Immunohistochemistry: 1.100-1.250

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: 0.1 M Tris-buffered saline with 10 % Glycerol (pH 7.0).0.01 % Thimerosal was added as a preservative.

Agent conservateur: Thimerosal (Merthiolate)

Précaution d'utilisation: Biohazard Informations: This product contains thimerosal which is hazardous.

Stock: 4 °C/-20 °C

Stockage commentaire: Store at -20 °C for long term preservation (recommended). Store at 4 °C for short term use.

Détails sur FGFRL1

Antigène: FGFRL1 (Fibroblast Growth Factor Receptor-Like 1 (FGFRL1))

Autre désignation: FGFR-5

Sujet: The protein encoded by this gene is a member of the fibroblast growth factor receptor (FGFR) family, where amino acid sequence is highly conserved between members and throughout evolution.FGFR family members differ from one another in their ligand affinities and tissue distribution.A full-length representative protein would consist of an extracellular region, composed of three immunoglobulin-like domains, a single hydrophobic membrane-spanning segment and a cytoplasmic tyrosine kinase domain.The extracellular portion of the protein interacts with fibroblast growth factors, setting in motion a cascade of downstream signals, ultimately influencing mitogenesis and differentiation.A marked difference between this gene product and the other family members is its lack of a cytoplasmic tyrosine kinase domain.The result is a transmembrane receptor that could interact with other family members and potentially inhibit signaling.Multiple alternatively spliced transcript variants encoding the same isoform have been found for this gene.[provided by RefSeq]

Poids moléculaire: 55 kDa

ID gène: 53834

NCBI Accession: NP_001004356, NM_001004356

Pathways: Signalisation RTK