FGFRL1 anticorps (N-Term)

N° du produit ABIN952316

L’anticorps anti-FGFRL1 Polyclonal Lapin est utilisé pour la détection de FGFRL1 dans des échantillons de Humain. Il a été validé pour WB et EIA.

Aperçu rapide pour FGFRL1 anticorps (N-Term) (ABIN952316)

Antigène: FGFRL1 (Fibroblast Growth Factor Receptor-Like 1 (FGFRL1))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp FGFRL1 est non-conjugé

Application: Western Blotting (WB), Enzyme Immunoassay (EIA)

Détail du produit anti-FGFRL1 anticorps

Épitope: N-Term

Specificité: This antibody reacts to FGFRL1.

Réactivité croisée (Details): Species reactivity (tested):Human.

Purification: Affinity chromatography on Protein A

Immunogène: The protein encoded by this gene is a member of the fibroblast growth factor receptor (FGFR) family, where amino acid sequence is highly conserved between members and throughout evolution. FGFR family members differ from one another in their ligand affinities and tissue distribution. A full-length representative protein would consist of an extracellular region, composed of three immunoglobulin-like domains, a single hydrophobic membrane-spanning segment and a cytoplasmic tyrosine kinase domain. The extracellular portion of the protein interacts with fibroblast growth factors, setting in motion a cascade of downstream signals, ultimately influencing mitogenesis and differentiation. A marked difference between this gene product and the other family members is its lack of a cytoplasmic tyrosine kinase domain. The result is a transmembrane receptor that could interact with other family members and potentially inhibit signaling. Multiple alternatively spliced transcript variants encoding the same isoform have been found for this gene.

Isotype: Ig Fraction

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.25 mg/mL

Buffer: PBS, 0.09 % (W/V) sodium azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: 4 °C/-20 °C

Stockage commentaire: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Détails sur FGFRL1

Antigène: FGFRL1 (Fibroblast Growth Factor Receptor-Like 1 (FGFRL1))

Autre désignation: FGFRL1

Sujet: Synonyms: FGF homologous factor receptor, FGFR-like protein, FGFR5, FHFR, Fibroblast growth factor receptor 5, Fibroblast growth factor receptor-like 1

Poids moléculaire: 54537 Da

ID gène: 53834

NCBI Accession: NP_001004356

Pathways: Signalisation RTK