CASP14 anticorps (AA 171-230)
Aperçu rapide pour CASP14 anticorps (AA 171-230) (ABIN1886107)
Antigène
Voir toutes CASP14 AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- AA 171-230
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Purification
- Purified by antigen-affinity chromatography.
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Immunogène
- Synthetic peptide contain a sequence corresponding to a region within amino acids 171 and 230 of Caspase 14
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Indications d'application
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Suggested dilutions:
Western blotting: 1.500-1.3000
Immunofluorescence: 1.100-1.200 -
Restrictions
- For Research Use only
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Format
- Liquid
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Buffer
- 0.1 M Tris-buffered saline with 10 % Glycerol (pH 7.0).0.01 % Thimerosal was added as a preservative.
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Agent conservateur
- Thimerosal (Merthiolate)
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Précaution d'utilisation
- Biohazard Informations: This product contains thimerosal which is hazardous.
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Stock
- 4 °C/-20 °C
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Stockage commentaire
- Store at -20 °C for long term preservation (recommended). Store at 4 °C for short term use.
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- CASP14 (Caspase 14, Apoptosis-Related Cysteine Peptidase (CASP14))
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Autre désignation
- Caspase 14
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Sujet
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This gene encodes a member of the cysteine-aspartic acid protease (caspase) family.Sequential activation of caspases plays a central role in the execution-phase of cell apoptosis.Caspases exist as inactive proenzymes which undergo proteolytic processing at conserved aspartic residues to produce two subunits, large and small, that dimerize to form the active enzyme.This caspase has been shown to be processed and activated by caspase 8 and caspase 10 in vitro, and by anti-Fas agonist antibody or TNF-related apoptosis inducing ligand in vivo.The expression and processing of this caspase may be involved in keratinocyte terminal differentiation, which is important for the formation of the skin barrier.[provided by RefSeq]
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Poids moléculaire
- 28 kDa
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ID gène
- 23581
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NCBI Accession
- NP_036246, NM_012114
Antigène
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