TPP1 anticorps (AA 224-562)
Aperçu rapide pour TPP1 anticorps (AA 224-562) (ABIN1886223)
Antigène
Voir toutes TPP1 AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- AA 224-562
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Purification
- Purified by antigen-affinity chromatography.
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Immunogène
- Recombinant protein fragment contain a sequence corresponding to a region within amino acids 224 and 562 of CLN2
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Indications d'application
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Suggested dilutions:
Western blotting: 1.500-1.3000 -
Restrictions
- For Research Use only
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Format
- Liquid
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Buffer
- 0.1 M Tris-buffered saline with 10 % Glycerol (pH 7.0).0.01 % Thimerosal was added as a preservative.
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Agent conservateur
- Thimerosal (Merthiolate)
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Précaution d'utilisation
- Biohazard Informations: This product contains thimerosal which is hazardous.
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Stock
- 4 °C/-20 °C
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Stockage commentaire
- Store at -20 °C for long term preservation (recommended). Store at 4 °C for short term use.
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- TPP1 (Tripeptidyl Peptidase I (TPP1))
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Autre désignation
- CLN2
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Sujet
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This gene encodes a member of the sedolisin family of serine proteases.The protease functions in the lysosome to cleave N-terminal tripeptides from substrates, and has weaker endopeptidase activity.It is synthesized as a catalytically-inactive enzyme which is activated and auto-proteolyzed upon acidification.Mutations in this gene result in late-infantile neuronal ceroid lipofuscinosis, which is associated with the failure to degrade specific neuropeptides and a subunit of ATP synthase in the lysosome.[provided by RefSeq]
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Poids moléculaire
- 61 kDa
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ID gène
- 1200
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NCBI Accession
- NP_000382, NM_000391
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Pathways
- Cycle Cellulaire, ER-Nucleus Signaling
Antigène
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