IL12RB2 anticorps (AA 323-665)

N° du produit ABIN1886370

Cet anticorps anti-IL12RB2 est un anticorps Lapin Polyclonal détectant IL12RB2 dans WB. Adapté pour Humain.

Aperçu rapide pour IL12RB2 anticorps (AA 323-665) (ABIN1886370)

Antigène: IL12RB2 (Interleukin 12 Receptor, beta 2 (IL12RB2))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp IL12RB2 est non-conjugé

Application: Western Blotting (WB)

Détail du produit anti-IL12RB2 anticorps

Épitope: AA 323-665

Purification: Purified by antigen-affinity chromatography.

Immunogène: Recombinant protein fragment contain a sequence corresponding to a region within amino acids 323 and 665 of Human IL12RB2

Information d'application

Indications d'application: Suggested dilutions:
Western blotting: 1.500-1.3000

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: 0.1 M Tris-buffered saline with 10 % Glycerol (pH 7.0).0.01 % Thimerosal was added as a preservative.

Agent conservateur: Thimerosal (Merthiolate)

Précaution d'utilisation: Biohazard Informations: This product contains thimerosal which is hazardous.

Stock: 4 °C/-20 °C

Stockage commentaire: Store at -20 °C for long term preservation (recommended). Store at 4 °C for short term use.

Détails sur IL12RB2

Antigène: IL12RB2 (Interleukin 12 Receptor, beta 2 (IL12RB2))

Sujet: The protein encoded by this gene is a type I transmembrane protein identified as a subunit of the interleukin 12 receptor complex.The coexpression of this and IL12RB1 proteins was shown to lead to the formation of high-affinity IL12 binding sites and reconstitution of IL12 dependent signaling.The expression of this gene is up-regulated by interferon gamma in Th1 cells, and plays a role in Th1 cell differentiation.The up-regulation of this gene is found to be associated with a number of infectious diseases, such as Crohn's disease and leprosy, which is thought to contribute to the inflammatory response and host defense.[provided by RefSeq]

Poids moléculaire: 97 kDa

ID gène: 3595

NCBI Accession: NM_001559, NP_001550

Pathways: Signalistation JAK/STAT