FGD4 anticorps (AA 49-297)

N° du produit ABIN1886512

Cet anticorps Lapin Polyclonal détecte spécifiquement FGD4 dans WB, IF et IHC. Il présente une réactivité envers Humain.

Aperçu rapide pour FGD4 anticorps (AA 49-297) (ABIN1886512)

Antigène: FGD4 (FYVE, RhoGEF and PH Domain Containing 4 (FGD4))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp FGD4 est non-conjugé

Application: Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (IHC)

Détail du produit anti-FGD4 anticorps

Épitope: AA 49-297

Purification: Purified by antigen-affinity chromatography.

Immunogène: Recombinant protein fragment contain a sequence corresponding to a region within amino acids 49 and 297 of FGD4

Information d'application

Indications d'application: Suggested dilutions:
Western blotting: 1.500-1.3000
Immunohistochemistry: 1.100-1.500
Immunofluorescence: 1.100-1.200

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: 0.1 M Tris-buffered saline with 10 % Glycerol (pH 7.0).0.01 % Thimerosal was added as a preservative.

Agent conservateur: Thimerosal (Merthiolate)

Précaution d'utilisation: Biohazard Informations: This product contains thimerosal which is hazardous.

Stock: 4 °C/-20 °C

Stockage commentaire: Store at -20 °C for long term preservation (recommended). Store at 4 °C for short term use.

Détails sur FGD4

Antigène: FGD4 (FYVE, RhoGEF and PH Domain Containing 4 (FGD4))

Autre désignation: FGD4

Sujet: This gene encodes a protein that is involved in the regulation of the actin cytoskeleton and cell shape.This protein contains an actin filament-binding domain, which together with its Dbl homology domain and one of its pleckstrin homology domains, can form microspikes.This protein can activate MAPK8 independently of the actin filament-binding domain, and it is also involved in the activation of CDC42 via the exchange of bound GDP for free GTP.The activation of CDC42 also enables this protein to play a role in mediating the cellular invasion of Cryptosporidium parvum, an intracellular parasite that infects the gastrointestinal tract.Mutations in this gene can cause Charcot-Marie-Tooth disease type 4H (CMT4H), a disorder of the peripheral nervous system.[provided by RefSeq]

Poids moléculaire: 87 kDa

ID gène: 121512

NCBI Accession: NM_139241, NP_640334

Pathways: Neurotrophin Signaling Pathway