FGD4 anticorps (AA 49-297)
-
- Antigène Voir toutes FGD4 Anticorps
- FGD4 (FYVE, RhoGEF and PH Domain Containing 4 (FGD4))
-
Épitope
- AA 49-297
-
Reactivité
- Humain
-
Hôte
- Lapin
-
Clonalité
- Polyclonal
-
Conjugué
- Cet anticorp FGD4 est non-conjugé
-
Application
- Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (IHC)
- Purification
- Purified by antigen-affinity chromatography.
- Immunogène
- Recombinant protein fragment contain a sequence corresponding to a region within amino acids 49 and 297 of FGD4
- Top Product
- Discover our top product FGD4 Anticorps primaire
-
-
- Indications d'application
-
Suggested dilutions:
Western blotting: 1.500-1.3000
Immunohistochemistry: 1.100-1.500
Immunofluorescence: 1.100-1.200 - Restrictions
- For Research Use only
-
- Format
- Liquid
- Buffer
- 0.1 M Tris-buffered saline with 10 % Glycerol (pH 7.0).0.01 % Thimerosal was added as a preservative.
- Agent conservateur
- Thimerosal (Merthiolate)
- Précaution d'utilisation
- Biohazard Informations: This product contains thimerosal which is hazardous.
- Stock
- 4 °C/-20 °C
- Stockage commentaire
- Store at -20 °C for long term preservation (recommended). Store at 4 °C for short term use.
-
- Antigène
- FGD4 (FYVE, RhoGEF and PH Domain Containing 4 (FGD4))
- Autre désignation
- FGD4 (FGD4 Produits)
- Synonymes
- anticorps CMT4H, anticorps FRABP, anticorps ZFYVE6, anticorps 9030023J02Rik, anticorps 9330209B17Rik, anticorps Frabp, anticorps FYVE, RhoGEF and PH domain containing 4, anticorps FGD4, anticorps Fgd4
- Sujet
-
This gene encodes a protein that is involved in the regulation of the actin cytoskeleton and cell shape.This protein contains an actin filament-binding domain, which together with its Dbl homology domain and one of its pleckstrin homology domains, can form microspikes.This protein can activate MAPK8 independently of the actin filament-binding domain, and it is also involved in the activation of CDC42 via the exchange of bound GDP for free GTP.The activation of CDC42 also enables this protein to play a role in mediating the cellular invasion of Cryptosporidium parvum, an intracellular parasite that infects the gastrointestinal tract.Mutations in this gene can cause Charcot-Marie-Tooth disease type 4H (CMT4H), a disorder of the peripheral nervous system.[provided by RefSeq]
- Poids moléculaire
- 87 kDa
- ID gène
- 121512
- NCBI Accession
- NM_139241, NP_640334
- Pathways
- Neurotrophin Signaling Pathway
-