NAPA anticorps (AA 78-269)
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- Antigène Voir toutes NAPA Anticorps
- NAPA (N-Ethylmaleimide-Sensitive Factor Attachment Protein, alpha (NAPA))
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Épitope
- AA 78-269
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Reactivité
- Humain
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Hôte
- Lapin
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Clonalité
- Polyclonal
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Conjugué
- Cet anticorp NAPA est non-conjugé
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Application
- Western Blotting (WB), Immunofluorescence (IF)
- Purification
- Purified by antigen-affinity chromatography.
- Immunogène
- Recombinant protein fragment contain a sequence corresponding to a region within amino acids 78 and 269 of Human NAPA
- Top Product
- Discover our top product NAPA Anticorps primaire
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- Indications d'application
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Suggested dilutions:
Western blotting: 1.500-1.3000
Immunofluorescence: 1.100-1.200 - Restrictions
- For Research Use only
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- Format
- Liquid
- Buffer
- 0.1 M Tris-buffered saline with 10 % Glycerol (pH 7.0).0.01 % Thimerosal was added as a preservative.
- Agent conservateur
- Thimerosal (Merthiolate)
- Précaution d'utilisation
- Biohazard Informations: This product contains thimerosal which is hazardous.
- Stock
- 4 °C/-20 °C
- Stockage commentaire
- Store at -20 °C for long term preservation (recommended). Store at 4 °C for short term use.
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- Antigène
- NAPA (N-Ethylmaleimide-Sensitive Factor Attachment Protein, alpha (NAPA))
- Autre désignation
- alpha SNAP (NAPA Produits)
- Synonymes
- anticorps SNAPA, anticorps wu:fa26c04, anticorps zgc:63906, anticorps napb, anticorps 1500039N14Rik, anticorps AW209189, anticorps RA81, anticorps SNARE, anticorps a-SNAP, anticorps hyh, anticorps alpha-SNAP, anticorps Alpha-SNAP, anticorps NSF attachment protein alpha, anticorps N-ethylmaleimide-sensitive factor attachment protein, alpha b, anticorps NSF attachment protein alpha L homeolog, anticorps N-ethylmaleimide-sensitive factor attachment protein, alpha, anticorps N-ethylmaleimide sensitive fusion protein attachment protein alpha, anticorps soluble NSF attachment protein, anticorps NAPA, anticorps napab, anticorps napa.L, anticorps napa, anticorps EHI_000300, anticorps Napa, anticorps LOC102577508
- Sujet
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The 'SNARE hypothesis' is a model explaining the process of docking and fusion of vesicles to their target membranes.According to this model, membrane proteins from the vesicle (v-SNAREs) and proteins from the target membrane (t-SNAREs) govern theof vesicle targeting and docking through mutual recognition.Once the 2 classes of SNAREs bind to each other, they form a complex that recruits the general elements of the fusion apparatus, namely NSF (N-ethylmaleimide-sensitive factor) and SNAPs (soluble NSF-attachment proteins), to the site of membrane fusion, thereby forming the 20S fusion complex.Alpha- and gamma-SNAP are found in a wide range of tissues and act synergistically in intra-Golgi transport.The sequence of the predicted 295-amino acid human protein encoded by NAPA shares 37%, 60%, and 67% identity with the sequences of yeast, Drosophila, and squid alpha-SNAP, respectively.Platelets contain some of the same proteins, including NSF, p115/TAP, alpha-SNAP, gamma-SNAP, and the t-SNAREs syntaxin-2 and syntaxin-4, that are used in many vesicular transport processes in other cell types.Platelet exocytosis uses a molecular mechanism similar to that used by other secretory cells, such as neurons, although the proteins used by the platelet and their modes of regulation may be quite different.[provided by RefSeq]
- Poids moléculaire
- 33 kDa
- ID gène
- 8775
- NCBI Accession
- NM_003827, NP_003818
- Pathways
- Synaptic Vesicle Exocytosis, Asymmetric Protein Localization
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