DUSP6 anticorps (AA 82-340)

N° du produit ABIN1886675

L’anticorps anti-DUSP6 Polyclonal Lapin est utilisé pour la détection de DUSP6 dans des échantillons de Humain. Il a été validé pour WB.

Aperçu rapide pour DUSP6 anticorps (AA 82-340) (ABIN1886675)

Antigène: DUSP6 (Dual Specificity Phosphatase 6 (DUSP6))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp DUSP6 est non-conjugé

Application: Western Blotting (WB)

Détail du produit anti-DUSP6 anticorps

Épitope: AA 82-340

Purification: Purified by antigen-affinity chromatography.

Immunogène: Recombinant protein fragment contain a sequence corresponding to a region within amino acids 82 and 340 of human DUSP6

Information d'application

Indications d'application: Suggested dilutions:
Western blotting: 1.500-1.3000

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: 0.1 M Tris-buffered saline with 10 % Glycerol (pH 7.0).0.01 % Thimerosal was added as a preservative.

Agent conservateur: Thimerosal (Merthiolate)

Précaution d'utilisation: Biohazard Informations: This product contains thimerosal which is hazardous.

Stock: 4 °C/-20 °C

Stockage commentaire: Store at -20 °C for long term preservation (recommended). Store at 4 °C for short term use.

Détails sur DUSP6

Antigène: DUSP6 (Dual Specificity Phosphatase 6 (DUSP6))

Autre désignation: MKP-3

Sujet: The protein encoded by this gene is a member of the dualprotein phosphatase subfamily.These phosphatases inactivate their target kinases by dephosphorylating both the phosphoserine/threonine and phosphotyrosine residues.They negatively regulate members of the mitogen-activated protein (MAP) kinase superfamily (MAPK/ERK, SAPK/JNK, p38), which are associated with cellular proliferation and differentiation.Different members of the family of dualphosphatases show distinct substrate specificities for various MAP kinases, different tissue distribution and subcellular localization, and different modes of inducibility of their expression by extracellular stimuli.This gene product inactivates ERK2, is expressed in a variety of tissues with the highest levels in heart and pancreas, and unlike most other members of this family, is localized in the cytoplasm.Two transcript variants encoding different isoforms have been found for this gene.[provided by RefSeq]

Poids moléculaire: 42 kDa

ID gène: 1848

NCBI Accession: NM_001946, NP_001937

Pathways: Neurotrophin Signaling Pathway, Activation of Innate immune Response, Toll-Like Receptors Cascades