DIABLO anticorps (AA 222-237)

N° du produit ABIN1886858

Détail du produit anti-DIABLO anticorps

Antigène: DIABLO (Second Mitochondria-Derived Activator of Caspase (DIABLO))

Épitope: AA 222-237

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp DIABLO est non-conjugé

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Purification: Affinity chromatography purified via peptide column

Immunogène: Peptide corresponding to amino acids 222 to 237 of murine Smac/DIABLO.

Information d'application

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: PBS containing 0.02 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: WARNING: Reagents contain sodium azide. Sodium azide is very toxic if ingested or inhaled. Avoid contact with skin, eyes, or clothing. Wear eye or face protection when handling. If skin or eye contact occurs, wash with copious amounts of water. If ingested or inhaled, contact a physician immediately. Sodium azide yields toxic hydrazoic acid under acidic conditions. Dilute azide-containing compounds in running water before discarding to avoid accumulation of potentially explosive deposits in lead or copper plumbing.

Conseil sur la manipulation: Avoid freezing and thawing repeatly.

Stock: 4 °C/-20 °C

Stockage commentaire: Store at 4 °C for short term use.Store at -20 °C for long term preservation.

Détails sur DIABLO

Antigène: DIABLO (Second Mitochondria-Derived Activator of Caspase (DIABLO))

Autre désignation: Smac (DIABLO Produits)

Synonymes: anticorps smac, anticorps smac3, anticorps diablo-s, anticorps 0610041G12Rik, anticorps 1700006L01Rik, anticorps AU040403, anticorps Smac, anticorps DFNA64, anticorps SMAC, anticorps DBO, anticorps XSmac, anticorps diablo, IAP-binding mitochondrial protein, anticorps diablo IAP-binding mitochondrial protein, anticorps diablo, IAP-binding mitochondrial protein L homeolog, anticorps diablo, anticorps Diablo, anticorps DIABLO, anticorps diablo.L

Sujet: The inhibitor of apoptosis proteins (IAPs) regulate programmed cell death by inhibiting members of the caspase family of enzymes.A novel mammalian protein that binds to IAPs and neutralizes the inhibitory effect of IAPs on caspases was recently identified and designated Smac/DIABLO.Smac/DIABLO is a mitochondrial protein that is released along with cytochrome c during apoptosis and activates cytochrome c/Apaf-1/capase-9 pathway.Analysis of the structural basis of Smac/DIABLO reveals that the N-terminal amino acids are required for binding of Smac/DIABLO to IAPs and activation of caspases.Smac/DIABLO is expressed in a variety of human and mouse tissues.
Synonyms: DIABLO, mSmac

Poids moléculaire: 25 kDa

Pathways: Apoptose, Caspase Cascade in Apoptosis, Positive Regulation of Endopeptidase Activity