IL21 Receptor anticorps (AA 97-111)
Aperçu rapide pour IL21 Receptor anticorps (AA 97-111) (ABIN1886904)
Antigène
Voir toutes IL21 Receptor (IL21R) AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- AA 97-111
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Purification
- Affinity chromatography purified via peptide column
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Immunogène
- Synthetic peptide corresponding to amino acids 97 to 111 of human IL-21 receptor precursor.
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Restrictions
- For Research Use only
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Format
- Liquid
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Buffer
- PBS containing 0.02 % sodium azide.
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- WARNING: Reagents contain sodium azide. Sodium azide is very toxic if ingested or inhaled. Avoid contact with skin, eyes, or clothing. Wear eye or face protection when handling. If skin or eye contact occurs, wash with copious amounts of water. If ingested or inhaled, contact a physician immediately. Sodium azide yields toxic hydrazoic acid under acidic conditions. Dilute azide-containing compounds in running water before discarding to avoid accumulation of potentially explosive deposits in lead or copper plumbing.
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Conseil sur la manipulation
- Avoid freezing and thawing repeatly.
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Stock
- 4 °C/-20 °C
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Stockage commentaire
- Store at 4 °C for short term use.Store at -20 °C for long term preservation.
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- IL21 Receptor (IL21R) (Interleukin 21 Receptor (IL21R))
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Autre désignation
- IL-21 Receptor
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Sujet
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A novel cytokine related to IL-2 and IL-15 was recently identified and designated IL-21.The receptor for IL-21 (IL-21R, also termed NILR for novel Interleukin receptor) is a new member of the class I cytokine receptor family.IL-21R forms a complex with the common cytokine receptor gamma chain, gammac, and mediates IL-21 signaling.Both IL-21R and the gammac are necessary for the IL-21 function.IL-21 and its receptor activate JAK-STAT signaling pathway.IL-21R is expressed in spleen, thymus, natural killer (NK), T and B cell lines.IL-21 plays a role in the proliferation and maturation of NK, B and T cell populations.
Synonyms: IL21R -
Poids moléculaire
- 60 kDa
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NCBI Accession
- NP_068570
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Pathways
- Signalistation JAK/STAT
Antigène
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