L’anticorps Lapin Polyclonal anti-TCL1A a été validé pour WB et FACS. Il convient pour détecter TCL1A dans des échantillons de Humain. Il y a 3+ publications disponibles.
This antibody is purified through a protein A column, followed by peptide affinity purification.
Immunogène
This TCL1A antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 32-66 amino acids from the Central region of human TCL1A.
TCL1A
Reactivité: Humain, Rat, Souris
WB, IHC, ELISA
Hôte: Lapin
Polyclonal
unconjugated
Indications d'application
WB: 1:1000. FC: 1:25
Restrictions
For Research Use only
Format
Liquid
Buffer
Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
Agent conservateur
Sodium azide
Précaution d'utilisation
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Stock
4 °C,-20 °C
Date de péremption
6 months
Laine, Künstle, Obata, Sha, Noguchi: "The protooncogene TCL1 is an Akt kinase coactivator." dans: Molecular cell, Vol. 6, Issue 2, pp. 395-407, (2000) (PubMed).
Virgilio, Narducci, Isobe, Billips, Cooper, Croce, Russo: "Identification of the TCL1 gene involved in T-cell malignancies." dans: Proceedings of the National Academy of Sciences of the United States of America, Vol. 91, Issue 26, pp. 12530-4, (1995) (PubMed).
Fu, Virgilio, Narducci, Facchiano, Russo, Croce: "Characterization and localization of the TCL-1 oncogene product." dans: Cancer research, Vol. 54, Issue 24, pp. 6297-301, (1995) (PubMed).
Antigène
TCL1A
(T-Cell Leukemia/lymphoma 1A (TCL1A))
Autre désignation
TCL1A
Sujet
Enhances the phosphorylation and activation of AKT1, AKT2 and AKT3. Promotes nuclear translocation of AKT1. Enhances cell proliferation, stabilizes mitochondrial membrane potential and promotes cell survival.