C1S anticorps

N° du produit ABIN1944822

Détail du produit anti-C1S anticorps

Antigène: C1S (Complement Component 1, S Subcomponent (C1S))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp C1S est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Isotype: IgG1

Information d'application

Indications d'application: WB: 1:500-1:1000. IHC: 1:50-1:100

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Agent conservateur: Sodium azide

Précaution d'utilisation: WARNING: Reagents contain sodium azide. Sodium azide is very toxic if ingested or inhaled. Avoid contact with skin, eyes, or clothing. Wear eye or face protection when handling. If skin or eye contact occurs, wash with copious amounts of water. If ingested or inhaled, contact a physician immediately. Sodium azide yields toxic hydrazoic acid under acidic conditions. Dilute azide-containing compounds in running water before discarding to avoid accumulation of potentially explosive deposits in lead or copper plumbing.

Stock: 4 °C,-20 °C

Références pour anticorps anti-C1S (ABIN1944822)

Endo, Takahashi, Nakao, Saiga, Sekine, Matsushita, Nonaka, Fujita: "Two lineages of mannose-binding lectin-associated serine protease (MASP) in vertebrates." dans: Journal of immunology (Baltimore, Md. : 1950), Vol. 161, Issue 9, pp. 4924-30, (1998) (PubMed).

Mackinnon, Carter, Smyth, Dunbar, Fothergill: "Molecular cloning of cDNA for human complement component C1s. The complete amino acid sequence." dans: European journal of biochemistry / FEBS, Vol. 169, Issue 3, pp. 547-53, (1988) (PubMed).

Kusumoto, Hirosawa, Salier, Hagen, Kurachi: "Human genes for complement components C1r and C1s in a close tail-to-tail arrangement." dans: Proceedings of the National Academy of Sciences of the United States of America, Vol. 85, Issue 19, pp. 7307-11, (1988) (PubMed).

Tosi, Duponchel, Meo, Julier: "Complete cDNA sequence of human complement Cls and close physical linkage of the homologous genes Cls and Clr." dans: Biochemistry, Vol. 26, Issue 26, pp. 8516-24, (1988) (PubMed).

Détails sur C1S

Antigène: C1S (Complement Component 1, S Subcomponent (C1S))

Autre désignation: C1S (C1S Produits)

Synonymes: anticorps AA959438, anticorps AI255193, anticorps AI327365, anticorps C1sa, anticorps r-gsp, anticorps C1S, anticorps complement C1s, anticorps complement component 1, s subcomponent 1, anticorps complement component 1, s subcomponent, anticorps complement component 1, s subcomponent L homeolog, anticorps complement C1s subcomponent, anticorps C1S, anticorps C1s1, anticorps C1s, anticorps c1s, anticorps c1s.L, anticorps LOC100558615

Sujet: C1s B chain is a serine protease that combines with C1q and C1r to form C1, the first component of the classical pathway of the complement system. C1r activates C1s so that it can, in turn, activate C2 and C4.

Poids moléculaire: 76684 Da

ID gène: 716

UniProt: P09871

Pathways: Système du Complément