FOXO4 anticorps (Ser197)

N° du produit ABIN197368

Cet anticorps Lapin Polyclonal détecte spécifiquement FOXO4 dans WB et IHC (p). Il présente une réactivité envers Humain, Souris et Rat.

Aperçu rapide pour FOXO4 anticorps (Ser197) (ABIN197368)

Antigène: FOXO4 (Forkhead Box O4 (FOXO4))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp FOXO4 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Détail du produit anti-FOXO4 anticorps

Épitope: Ser197

Specificité: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. AFX antibody AP02683PU detects endogenous levels of total AFX protein.

Purification: Immunoaffinity chromatography.

Immunogène: The antiserum was produced against synthesized non-phosphopeptide derived from human AFX around the phosphorylation site of serine 197 (A-A-Sp-M-D).

Information d'application

Indications d'application: Suitable for use in Western blot (1: 500-1: 1000) and Immunohistochemistry (1: 50-1: 100).
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Stockage

Concentration: 1.0 mg/mL

Buffer: PBS (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % Sodium Azide and 50 % Glycerol.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: -20 °C

Stockage commentaire: Store the antibody (in aliquots) at -20 °C.

Détails sur FOXO4

Antigène: FOXO4 (Forkhead Box O4 (FOXO4))

Autre désignation: FOXO4 / AFX1 / MLLT7

Sujet: FOXO4 is a forkhead transcription factor involved in the regulation of the insulin signaling pathway. It binds to insulin-response elements (IREs) and can activate transcription of IGFBP1. FOXO4 down-regulates expression of HIF1A and suppresses hypoxia-induced transcriptional activation of HIF1A-modulated genes. It is also involved in negative regulation of the cell cycle.Synonyms: Fork head domain transcription factor AFX1, Forkhead box protein O4

ID gène: 4303

NCBI Accession: NP_001164402

UniProt: P98177

Pathways: Cycle Cellulaire, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Regulation of Muscle Cell Differentiation