GZMA anticorps

N° du produit ABIN198300

Cet anticorps anti-GZMA Monoclonal Souris (Clone GA6) (ABIN198300) détecte spécifiquement GZMA dans WB, IHC et IHC (p). L’anticorps est réactif avec des échantillons de Humain.

Aperçu rapide pour GZMA anticorps (ABIN198300)

Antigène: GZMA (Granzyme A (Granzyme 1, Cytotoxic T-Lymphocyte-Associated serine Esterase 3) (GZMA))

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp GZMA est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Clone: GA6

Détail du produit anti-GZMA anticorps

Specificité: Recognizes Granzyme A, a 60kD disulphide-linked homodimeric protein expressed in cytoplasmic granules of cytotoxic lymphocytes. The biological function of Granzyme A is unclear. It would appear that the molecule may have a role in the induction of apoptosis via its activity as a serine protease, but this would seem to be subsidiary to the role of Granzyme B. Granzyme A deficient mice are indistinguishable from normal animals in their response to infection.

Purification: Affinity purified

Immunogène: Recombinant human granzyme A.

Type of Immunogen: Recombinant protein

Isotype: IgG1

Information d'application

Indications d'application: Approved: IHC, IHC-P (1:50 - 1:200), WB

Usage: Immunohistology: This product requires antigen retrieval using heat treatment prior to staining of paraffin sections. Sodium citrate buffer  pH 6.0 is recommended for this purpose.

Commentaires:

Target Species of Antibody: Human

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: PBS, 0.09 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freezing and thawing. Store undiluted.

Stock: 4 °C,-20 °C

Stockage commentaire: 4°C or -20°C, Avoid freeze-thaw cycles. Store undiluted.

Détails sur GZMA

Antigène: GZMA (Granzyme A (Granzyme 1, Cytotoxic T-Lymphocyte-Associated serine Esterase 3) (GZMA))

Autre désignation: GZMA / Granzyme A

Sujet: Name/Gene ID: GZMA
Subfamily: Serine S1
Family: Protease

Synonyms: GZMA, CTLA3, CTL tryptase, Granzyme-1, H factor, HF, HFSP, Granzyme A, Fragmentin-1, Hanukah factor, Hanukkah factor

ID gène: 3001

Pathways: Apoptose