GZMA anticorps (AA 29-262)

N° du produit ABIN7154414

Détail du produit anti-GZMA anticorps

Antigène: GZMA (Granzyme A (Granzyme 1, Cytotoxic T-Lymphocyte-Associated serine Esterase 3) (GZMA))

Épitope: AA 29-262

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp GZMA est non-conjugé

Application: ELISA, Immunohistochemistry (IHC)

Réactivité croisée: Humain

Purification: Antigen Affinity Purified

Immunogène: Recombinant Human Granzyme A protein (29-262AA)

Isotype: IgG

Information d'application

Indications d'application: Recommended dilution: IHC:1:20-1:200,

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C,-80 °C

Stockage commentaire: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Détails sur GZMA

Antigène: GZMA (Granzyme A (Granzyme 1, Cytotoxic T-Lymphocyte-Associated serine Esterase 3) (GZMA))

Autre désignation: GZMA (GZMA Produits)

Synonymes: anticorps gzmA, anticorps GZMA, anticorps AW494114, anticorps Ctla-3, anticorps Ctla3, anticorps Hf, anticorps SE1, anticorps TSP-1, anticorps TSP1, anticorps CTLA3, anticorps HFSP, anticorps granzyme A, anticorps Granzyme A, anticorps granzyme A (granzyme 1, cytotoxic T-lymphocyte-associated serine esterase 3), anticorps gzmA, anticorps GZMA, anticorps graa, anticorps Gzma

Sujet:

Background: Abundant protease in the cytosolic granules of cytotoxic T-cells and NK-cells which activates caspase-independent cell death with morphological features of apoptosis when delivered into the target cell through the immunological synapse. It cleaves after Lys or Arg. Cleaves APEX1 after \\\'Lys-31\\\' and destroys its oxidative repair activity. Cleaves the nucleosome assembly protein SET after \\\'Lys-189\\\', which disrupts its nucleosome assembly activity and allows the SET complex to translocate into the nucleus to nick and degrade the DNA.

Aliases: CTL tryptase antibody, CTLA3 antibody, Cytolytic t cell and natural killer cell specific trypsin like serine protease antibody, Cytotoxic T lymphocyte associated serine esterase 3 antibody, Cytotoxic T lymphocyte proteinase 1 antibody, Cytotoxic T-lymphocyte proteinase 1 antibody, Fragmentin 1 antibody, Fragmentin-1 antibody, GRAA_HUMAN antibody, Granzyme 1 cytotoxic T lymphocyte associated serine esterase 3 antibody, Granzyme A (Cytotoxic T lymphocyte associated serine esterase 3, Hanukah factor serine protease) antibody, Granzyme A (granzyme 1, cytotoxic T lymphocyte associated serine esterase 3) antibody, Granzyme A antibody, Granzyme A precursor antibody, Granzyme-1 antibody, GZMA antibody, H factor antibody, Hanukah factor serine protease antibody, Hanukkah factor antibody, HF antibody, HFSP antibody, TSP1 antibody

UniProt: P12544

Pathways: Apoptose