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Connexin 43/GJA1 anticorps (C-Term)

Cet anticorps anti-Connexin 43/GJA1 est un anticorps Souris Monoclonal détectant Connexin 43/GJA1 dans WB, ELISA, IF et IHC (p). Adapté pour Humain, Rat, Souris et Chien.
N° du produit ABIN199020

Aperçu rapide pour Connexin 43/GJA1 anticorps (C-Term) (ABIN199020)

Antigène

Voir toutes Connexin 43/GJA1 (GJA1) Anticorps
Connexin 43/GJA1 (GJA1) (Gap Junction Protein, alpha 1, 43kDa (GJA1))

Reactivité

  • 127
  • 86
  • 84
  • 32
  • 11
  • 10
  • 10
  • 9
  • 8
  • 7
  • 6
  • 4
  • 4
  • 3
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
Humain, Rat, Souris, Chien

Hôte

  • 133
  • 8
  • 3
  • 2
Souris

Clonalité

  • 136
  • 9
Monoclonal

Conjugué

  • 89
  • 6
  • 4
  • 4
  • 4
  • 4
  • 4
  • 4
  • 3
  • 3
  • 2
  • 2
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
Cet anticorp Connexin 43/GJA1 est non-conjugé

Application

  • 105
  • 64
  • 49
  • 22
  • 20
  • 19
  • 18
  • 17
  • 13
  • 13
  • 7
  • 6
  • 2
  • 2
  • 1
  • 1
  • 1
Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
  • Épitope

    • 18
    • 16
    • 11
    • 8
    • 8
    • 8
    • 7
    • 7
    • 7
    • 4
    • 4
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    C-Term

    Specificité

    Recognizes rat Connexin 43 only when the serine at residue 368 is unphosphorylated. Does recognize Connexin 43 if it is phosphorylated at sites other than Ser368. In some cell types, cross-reactivity with a ~70kD protein of unknown identity has been observed. This cross-reactivity is likely due to a shared epitope. Species cross-reactivity: Canine, human, mouse.

    Purification

    Immunoaffinity purified

    Immunogène

    Synthetic peptide corresponding to a cytoplasmic sequence located near the C-terminus of rat Connexin 43.

    Type of Immunogen: Synthetic peptide

    Isotype

    IgG1 kappa
  • Indications d'application

    Suitable for use in Immunofluorescence, ELISA, Western Blot, Immunolocalization and Electron Microscopy. ELISA: 0.1-1 ug/ml. Western Blot: 1-3 ug/ml.

    Commentaires

    Target Species of Antibody: Rat

    Restrictions

    For Research Use only
  • Format

    Liquid

    Concentration

    Lot specific

    Buffer

    PBS,  pH 7.4, 0.1 % sodium azide

    Agent conservateur

    Sodium azide

    Précaution d'utilisation

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    Conseil sur la manipulation

    Avoid repeated freezing and thawing.

    Stock

    4 °C,-20 °C

    Stockage commentaire

    4°C or -20°C, Avoid freeze-thaw cycles.
  • Antigène

    Connexin 43/GJA1 (GJA1) (Gap Junction Protein, alpha 1, 43kDa (GJA1))

    Autre désignation

    GJA1 / CX43 / Connexin 43

    Sujet

    Name/Gene ID: GJA1
    Subfamily: Connexin
    Family: Ion Channel

    Synonyms: GJA1, Connexin-43, DFNB38, Connexin 43, Gap junction alpha-1 protein, GJAL, HSS, Gap junction protein alpha 1, ODDD, ODD, AVSD3, CX43, HLHS1, ODOD, SDTY3

    ID gène

    2697

    UniProt

    P17302

    Pathways

    Signalisation MAPK, Myometrial Relaxation and Contraction, Cell-Cell Junction Organization
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