C9 anticorps
Aperçu rapide pour C9 anticorps (ABIN206672)
Antigène
Voir toutes C9 AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Specificité
- Recognizes complement component 9 (C9), a 71kD member of the complement C6/C7/C8/C9 family present in the blood serum and synthesized by the liver and monocytes. C9 is the last component to be added during the formation of the membrane attack complex (MAC), binding the membrane associated C5b-8 complex and resulting in the circular polymerization of 12-18 C9 Molecules. This forms the hydrophilic transmembrane channel which causes cell lysis. Deficiency of C9 is associated with recurring infections by Neisseria meningitides. Does not recognize MAC.
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Purification
- Protein A purified
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Immunogène
- Purified human C9.
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Isotype
- IgG2b
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Indications d'application
- Optimal working dilution should be determined by the investigator.
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Commentaires
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Target Species of Antibody: Human
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- Lot specific
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Buffer
- Borate buffered saline, pH 8.2 - 8.4, 0.02 % sodium azide.
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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- C9 (Complement Component C9 (C9))
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Autre désignation
- Complement C9
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Sujet
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Name/Gene ID: C9
Subfamily: Complement Component
Synonyms: C9, Complement C9, Complement component 9, Complement component C9 -
ID gène
- 735
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UniProt
- P02748
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Pathways
- Système du Complément
Antigène
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