ITGA6 anticorps

N° du produit ABIN206770

Cet anticorps Rat Monoclonal détecte spécifiquement ITGA6 dans FACS, IHC, IP et IHC (fro). Il présente une réactivité avec des échantillons de Humain, Souris, Chien, Porc, Mouton et Cynomolgus.

Aperçu rapide pour ITGA6 anticorps (ABIN206770)

Antigène: ITGA6 (Integrin, alpha 6 (ITGA6))

Reactivité: Humain, Souris, Chien, Porc, Mouton, Cynomolgus

Hôte: Rat

Clonalité: Monoclonal

Conjugué: Cet anticorp ITGA6 est non-conjugé

Application: Flow Cytometry (FACS), Immunohistochemistry (IHC), Immunoprecipitation (IP), Immunohistochemistry (Frozen Sections) (IHC (fro))

Détail du produit anti-ITGA6 anticorps

Specificité: Recognizes the CD49f-antigen, (VLA-6 alpha-chain). CD49f can form distinct complexes with either the CD29-antigen (VLA beta-chain), resulting in the VLA-6 (alpha-6 beta-1) complex, which is expressed on human platelets, or with the beta-4 integrin resulting in the alpha-6 beta-4 complex which is expressed on various human epithelial cells. Reacts with platelets, megakaryocytes, T lymphocytes and common Acute Lymphoblastic Leukemia cells (alpha-6 beta-1). In immunohistology this Reacts with epithelial cells of a variety of tissues, peripheral nerves, microvascular endothelial cells, placenta cyto- and syncytiotrophoblasts. Platelet VLA-6 functions as a laminin receptor. This clone has been reported to inhibit platelet adhesion to laminin.

Purification: Protein G purified

Immunogène: BALB/c mouse mammary tumor cells.

Type of Immunogen: Cells

Isotype: IgG2a

Information d'application

Indications d'application: Approved: Flo, IHC, IHC-Fr, IP

Usage: Flow Cytometry: Use 10 μL of the suggested working dilution to label 10^6 platelets in 100 μL. Method sheets are available on request.

Commentaires:

Target Species of Antibody: Human

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: PBS,  pH 7.4, 0.09 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Détails sur ITGA6

Antigène: ITGA6 (Integrin, alpha 6 (ITGA6))

Autre désignation: ITGA6/Integrin alpha 6/CD49f

Sujet: Name/Gene ID: ITGA6
Family: Integrin

Synonyms: ITGA6, CD49f, CD49f antigen, Integrin alpha6B, Integrin, alpha 6, Integrin alpha-6 precursor, VLA-6, Integrin alpha-6, ITGA6B

ID gène: 3655

Pathways: CXCR4-mediated Signaling Events, Brown Fat Cell Differentiation, Integrin Complex