ITGA6 anticorps (PE)
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- Antigène Voir toutes ITGA6 Anticorps
- ITGA6 (Integrin, alpha 6 (ITGA6))
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Reactivité
- Humain, Souris, Chien, Porc, Mouton, Cynomolgus
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Hôte
- Rat
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Clonalité
- Monoclonal
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Conjugué
- Cet anticorp ITGA6 est conjugé à/à la PE
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Application
- Flow Cytometry (FACS), Immunohistochemistry (IHC), Immunoprecipitation (IP), Immunohistochemistry (Frozen Sections) (IHC (fro))
- Specificité
- Recognizes CD49F (VLA-6 alpha chain), a 120kD cell surface glycoprotein that can form distinct complexes with CD29 (VLA beta-chain), resulting in the VLA-6 (alpha-6 beta-1) complex, which is expressed on human platelets, or with the beta-4 integrin resulting in the alpha-6 beta-4 complex which is expressed on various human epithelial cells. Clone Reacts with platelets, megakaryocytes, T lymphocytes and common Acute Lymphoblastic Leukemia cells (alpha-6 beta-1). In immunohistology the monoclonal Reacts with epithelial cells of a variety of tissues, peripheral nerves, microvascular endothelial cells, placenta cyto- and syncytotrophoblasts. VLA-6 is an important mediator of cell binding to laminin. Studies suggest that clone GoH3 specifically blocks the binding of cells to the E8 fragment of laminin. XXX recommend the use of MCA699XZ for this purpose.
- Purification
- Protein G purified
- Immunogène
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BALB/c mouse mammary tumor cells.
Type of Immunogen: Cells - Isotype
- IgG2a
- Top Product
- Discover our top product ITGA6 Anticorps primaire
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- Indications d'application
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Approved: Flo (1:1 - 1:5), IHC, IHC-Fr, IP
Usage: The applications listed have been tested for the unconjugated form of this product. Other forms have not been tested. Flow Cytometry: Use 10 μL of the suggested working dilution to label 10^6 platelets in 100 μL. Method sheets are available on request. - Commentaires
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Target Species of Antibody: Human
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Distilled Water.
- Concentration
- Lot specific
- Buffer
- Lyophilized powder from PBS, pH 7.4, 0.09 % sodium azide, 1 % BSA, 5 % sucrose.
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Stock
- 4 °C
- Stockage commentaire
- Store at 4°C. Do not freeze.
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- Antigène
- ITGA6 (Integrin, alpha 6 (ITGA6))
- Autre désignation
- ITGA6/Integrin Alpha 6/CD49f (ITGA6 Produits)
- Synonymes
- anticorps CD49f, anticorps ITGA6B, anticorps VLA-6, anticorps 5033401O05Rik, anticorps AI115430, anticorps Cd49f, anticorps ITGA6, anticorps inta6, anticorps im:6897425, anticorps itga6, anticorps si:dkey-32o22.1, anticorps wu:fb80g02, anticorps LOC100221694, anticorps si:dkey-18j14.1, anticorps wu:fl20e08, anticorps zgc:113088, anticorps integrin subunit alpha 6, anticorps integrin alpha 6, anticorps integrin subunit alpha 6 L homeolog, anticorps integrin, alpha 6a, anticorps integrin, alpha 6b, anticorps ITGA6, anticorps Itga6, anticorps itga6.L, anticorps itga6a, anticorps itga6b
- Sujet
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Name/Gene ID: ITGA6
Family: Integrin
Synonyms: ITGA6, CD49f, CD49f antigen, Integrin alpha6B, Integrin, alpha 6, Integrin alpha-6 precursor, VLA-6, Integrin alpha-6, ITGA6B - ID gène
- 3655
- UniProt
- P23229
- Pathways
- CXCR4-mediated Signaling Events, Brown Fat Cell Differentiation, Integrin Complex
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