ROCK1 anticorps (AA 1114-1126)

N° du produit ABIN207918

Cet anticorps anti-ROCK1 est un anticorps Souris Monoclonal détectant ROCK1 dans WB. Adapté pour Humain, Souris, Rat, Singe, Boeuf (Vache), Roussette (Chauve-souris), Chien et Cheval.

Aperçu rapide pour ROCK1 anticorps (AA 1114-1126) (ABIN207918)

Antigène: ROCK1 (rho-Associated, Coiled-Coil Containing Protein Kinase 1 (ROCK1))

Reactivité: Humain, Souris, Rat, Singe, Boeuf (Vache), Roussette (Chauve-souris), Chien, Cheval

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp ROCK1 est non-conjugé

Application: Western Blotting (WB)

Clone: 154C1465

Détail du produit anti-ROCK1 anticorps

Épitope: AA 1114-1126

Specificité: This mAb recognizes the cleaved C-terminus of ROCK-1. It does not recognize the full-length protein. Since ROCK-1 is cleaved by caspase-3 during apoptosis, this may be used for detection of apoptosis.

Homologie: Percent identity by BLAST analysis: Human, Chimpanzee, Gorilla, Gibbon, Monkey, Marmoset, Mouse, Rat, Elephant, Bovine, Dog, Bat, Horse, Opossum, Platypus (100%) Rabbit (92%) Chicken (85%).

Purification: Protein G purified

Immunogène: This antibody was generated by immunizing mice with a synthetic peptide sequence corresponding to residues 1114-1126 GNLPESRIEGWLS of human ROCK-1. Immunogen peptide sequence is adjacent to the caspase-3 cleavage site of ROCK-1. Percent identity by BLAST analysis: Human, Chimpanzee, Gorilla, Gibbon, Monkey, Marmoset, Mouse, Rat, Elephant, Bovine, Dog, Bat, Horse, Opossum, Platypus (100%), Rabbit (92%), Chicken (85%).

Type of Immunogen: Synthetic peptide

Isotype: IgG

Information d'application

Indications d'application: Approved: WB (1 - 2 μg/mL)

Not recommended for: IHC-P

Commentaires:

Target Species of Antibody: Human

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: PBS, 0.2 % gelatin, 0.05 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeat freeze-thaw cycles.

Stock: 4 °C,-20 °C

Stockage commentaire: Short term: 4°C. Long term: Store at -20°C. Avoid freeze-thaw cycles.

Détails sur ROCK1

Antigène: ROCK1 (rho-Associated, Coiled-Coil Containing Protein Kinase 1 (ROCK1))

Autre désignation: Rho Kinase / ROCK1

Sujet: Name/Gene ID: ROCK1
Subfamily: ROCK
Family: Protein Kinase

Synonyms: ROCK1, p160 Rho-associated kinase, p160ROCK, p160 ROCK-1, p160-ROCK, p160RhoK, Rho-associated kinase, RockI, Rok, Rok alpha, Rho-alpha kinase, p160 rho-kinase, Rho kinase, ROCK-I, Rokalpha

ID gène: 6093

UniProt: Q13464

Pathways: Dynamique des Microtubules, Signalisation WNT, M Phase, Maintenance of Protein Location, Signaling Events mediated by VEGFR1 and VEGFR2, Thromboxane A2 Receptor Signaling