TBK1 anticorps (AA 563-577)

N° du produit ABIN213888

Cet anticorps anti-TBK1 Monoclonal Souris (Clone 108A429 ) (ABIN213888) détecte spécifiquement TBK1 dans WB, IHC et IHC (p). L’anticorps est réactif avec des échantillons de Humain, Souris, Rat, Boeuf (Vache), Lapin, Porc, Singe, Chien, Cheval et Hamster.

Aperçu rapide pour TBK1 anticorps (AA 563-577) (ABIN213888)

Antigène: TBK1 (TANK-Binding Kinase 1 (TBK1))

Reactivité: Humain, Souris, Rat, Boeuf (Vache), Lapin, Porc, Singe, Chien, Cheval, Hamster

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp TBK1 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Clone: 108A429 

Détail du produit anti-TBK1 anticorps

Épitope: AA 563-577

Specificité: A synthetic peptide corresponding to amino acids 563-577 YYQFKKDKAERRLAYC of human TBK1. GenBank no. NP-037386.1 was used as immunogen. This sequence is 100 % conserved between human, mouse, rat, dog and cow.

Homologie: Percent identity by BLAST analysis: Human, Gorilla, Gibbon, Monkey, Marmoset, Mouse, Rat, Bovine, Dog, Hamster, Panda, Horse, Rabbit, Pig (100%) Elephant, Chicken, Platypus (93%) Bat, Turkey, Lizard (87%) Xenopus, Pufferfish, Zebrafish, Stickleback (80%).

Purification: Protein G purified

Immunogène: A synthetic peptide corresponding to amino acids 563-577 (YYQFKKDKAERRLAYC) of human TBK1 was used as immunogen for this antibody. This sequence is 100% conserved between human, mouse, rat, dog and cow. Percent identity by BLAST analysis: Human, Gorilla, Gibbon, Monkey, Marmoset, Mouse, Rat, Bovine, Dog, Hamster, Panda, Horse, Rabbit, Pig (100%), Elephant, Chicken, Platypus (93%), Bat, Turkey, Lizard (87%), Xenopus, Pufferfish, Zebrafish, Stickleback (80%).

Type of Immunogen: Synthetic peptide

Isotype: IgG1 kappa

Information d'application

Indications d'application: Approved: IHC, IHC-P (10 μg/mL), WB (1 - 2 μg/mL)

Usage: Immunohistochemistry: This antibody was validated for use in immunohistochemistry on a panel of 21 formalin-fixed, paraffin-embedded (FFPE) human tissues after heat induced antigen retrieval in  pH 6.0 citrate buffer. After incubation with the primary antibody, slides were incubated with biotinylated secondary antibody, followed by alkaline phosphatase-streptavidin and chromogen. The stained slides were evaluated by a pathologist to confirm staining specificity. The optimal working concentration for this antibody was determined to be 10 μg/mL.

Commentaires:

Target Species of Antibody: Human

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: PBS, 0.05 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Short term: 4°C. Long term: Store at -20°C. Avoid freeze-thaw cycles.

Détails sur TBK1

Antigène: TBK1 (TANK-Binding Kinase 1 (TBK1))

Autre désignation: NAK / TBK1

Sujet: Name/Gene ID: TBK1
Subfamily: IKAPPAB
Family: Protein Kinase

Synonyms: TBK1, T2K, NAK, NF-kappa-B-activating kinase, NF-kB-activating kinase, TANK-binding kinase 1

ID gène: 29110

UniProt: Q9UHD2

Pathways: Signalisation TLR, Activation of Innate immune Response, Hepatitis C, Toll-Like Receptors Cascades, SARS-CoV-2 Protein Interactome