Dopamine d2 Receptor anticorps (3rd Cytoplasmic Domain)
Aperçu rapide pour Dopamine d2 Receptor anticorps (3rd Cytoplasmic Domain) (ABIN215781)
Antigène
Voir toutes Dopamine d2 Receptor (DRD2) AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
-
-
Épitope
- 3rd Cytoplasmic Domain
-
Specificité
- Specific for Dopamine Receptor D2 short and long form. Species cross-reactivity: Monkey, mouse and rat.
-
Purification
- Affinity purified
-
Immunogène
- A 28 amino acid peptide sequence from the human D2 receptor within the cytoplasmic loop #3. The immunogen peptide shows no significant homology with other dopamine receptors (D1 and D3-D5). Species sequence Homology: Bovine, canine - 100%, Xenopus - 50%.
-
Isotype
- IgG
-
-
-
-
Indications d'application
-
Approved: ELISA (0.5 - 1 μg/mL), IHC, IP (1 - 10 μg/mL), WB (1:1000)
Usage: Suitable for use in Western Blot, Immunohistochemistry, Immunoprecipitation and ELISA. Western Blot: 1:1000. Detected Dopamine Receptor D2 on 10 μg of human brain lysates. Immunohistochemistry (Paraformaldehyde fixed sections): 2-10 μg/mL. Immunoprecipitation: 1-10 μg/mL. Using 100-400 μg of protein. An antibody made to this epitope has been shown to immunoprecipitate both the long and short forms. ELISA: 0.5-1.0 μg/mL. Positive control: Monkey brain tissue, rat brain lysate. -
Commentaires
-
Target Species of Antibody: Human
-
Restrictions
- For Research Use only
-
-
-
Format
- Liquid
-
Concentration
- Lot specific
-
Buffer
- PBS, pH 7.4, 0.1 % BSA.
-
Conseil sur la manipulation
- avoid freeze thaw cycles.
-
Stock
- 4 °C,-20 °C
-
Stockage commentaire
- Short term 4°C, long term aliquot and store at -20°C, avoid freeze-thaw cycles.
-
-
- Dopamine d2 Receptor (DRD2) (Dopamine Receptor D2 (DRD2))
-
Autre désignation
- DRD2 / Dopamine Receptor D2
-
Sujet
-
Name/Gene ID: DRD2
Subfamily: Dopamine
Family: GPCR
Synonyms: DRD2, D2 dopamine receptor, D2R, Dopamine receptor D2 isoform, Dopamine 2 receptor, D(2) dopamine receptor, D2DR, Dopamine D2 receptor, Dopamine receptor D2 -
ID gène
- 1813
-
UniProt
- P14416
-
Pathways
- Positive Regulation of Peptide Hormone Secretion, Negative Regulation of Hormone Secretion, cAMP Metabolic Process, Inositol Metabolic Process, Regulation of G-Protein Coupled Receptor Protein Signaling, Feeding Behaviour, Negative Regulation of Transporter Activity, Regulation of long-term Neuronal Synaptic Plasticity
Antigène
-