Dopamine d2 Receptor anticorps (3rd Cytoplasmic Domain)

N° du produit ABIN215782

Cet anticorps Lapin Polyclonal détecte spécifiquement Dopamine d2 Receptor dans WB et ELISA. Il présente une réactivité envers Rat et Chien.

Aperçu rapide pour Dopamine d2 Receptor anticorps (3rd Cytoplasmic Domain) (ABIN215782)

Antigène: Dopamine d2 Receptor (DRD2) (Dopamine Receptor D2 (DRD2))

Reactivité: Rat, Chien

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Dopamine d2 Receptor est non-conjugé

Application: Western Blotting (WB), ELISA

Détail du produit anti-Dopamine d2 Receptor anticorps

Épitope: 3rd Cytoplasmic Domain

Specificité: Recognizes rat Dopamine Receptor D2 long form. Recognizes canine D2R. Species sequence Homology: Human, bovine, and canine: 96 % , Xenopus: 64 %.

Purification: Immunoaffinity purified

Immunogène: A 27 amino acid peptide sequence from the rat D2 long form within the cytoplasmic loop #3. No significant homology with other receptors (D1, D2 short, and D3-D5).

Type of Immunogen: Synthetic peptide

Isotype: IgG

Information d'application

Indications d'application: Approved: ELISA (0.5 - 1 μg/mL), WB (1 - 10 μg/mL)

Usage: Suitable for use in Western Blot and ELISA. Western Blot: 1-10 μg/mL (Chemiluminescence technique). The predicted size of D2L form is approximately 50kD. However, additional bands at approximately 60 and 100kD, and others are typically seen in various tissues. Approximately 100-400 μg of membrane protein/lane should be loaded to visualize various bands. ELISA: 0.5-1.0 μg/mL (1 μg/mL immunogen peptide/well).

Commentaires:

Target Species of Antibody: Rat

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: 100 mM Tris,  pH 7.5, 0.2 % BSA, 0.05 % sodium azide, 40 % glycerol.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeat freeze-thaw cycles.

Stock: 4 °C,-20 °C

Stockage commentaire: Short term: 4°C. Long term: Store at -20°C. Avoid freeze-thaw cycles.

Détails sur Dopamine d2 Receptor

Antigène: Dopamine d2 Receptor (DRD2) (Dopamine Receptor D2 (DRD2))

Autre désignation: DRD2 / Dopamine Receptor D2

Sujet: Name/Gene ID: DRD2
Subfamily: Dopamine
Family: GPCR

Synonyms: DRD2, D2 dopamine receptor, D2R, Dopamine receptor D2 isoform, Dopamine 2 receptor, D(2) dopamine receptor, D2DR, Dopamine D2 receptor, Dopamine receptor D2

ID gène: 1813

UniProt: P14416

Pathways: Positive Regulation of Peptide Hormone Secretion, Negative Regulation of Hormone Secretion, cAMP Metabolic Process, Inositol Metabolic Process, Regulation of G-Protein Coupled Receptor Protein Signaling, Feeding Behaviour, Negative Regulation of Transporter Activity, Regulation of long-term Neuronal Synaptic Plasticity