ISL1 anticorps (PE)

N° du produit ABIN2177077

Cet anticorps Lapin Polyclonal détecte spécifiquement ISL1 dans WB. Il présente une réactivité envers Humain, Souris et Rat.

Aperçu rapide pour ISL1 anticorps (PE) (ABIN2177077)

Antigène: ISL1 (ISL LIM Homeobox 1 (ISL1))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp ISL1 est conjugé à/à la PE

Application: Western Blotting (WB)

Détail du produit anti-ISL1 anticorps (PE)

Réactivité croisée: Humain

Homologie: Mouse,Rat,Sheep,Horse,Chicken

Purification: Purified by Protein A.

Immunogène: KLH conjugated synthetic peptide derived from human Islet 1

Isotype: IgG

Information d'application

Indications d'application: FCM: (1:20-100)
Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Détails sur ISL1

Antigène: ISL1 (ISL LIM Homeobox 1 (ISL1))

Autre désignation: Islet 1

Sujet:

Synonyms: Insulin gene enhancer protein ISL 1, Insulin gene enhancer protein ISL-1, Insulin related protein, Isl 1, ISL LIM homeobox 1, ISL1, ISL1 transcription factor LIM homeodomain, ISL1 transcription factor, LIM/homeodomain islet 1, ISL1 transcription factor, LIM/homeodomain, ISL1_HUMAN, Islet-1, Islet1.

Background: This gene encodes a member of the LIM/homeodomain family of transcription factors. The encoded protein binds to the enhancer region of the insulin gene, among others, and may play an important role in regulating insulin gene expression. The encoded protein is central to the development of pancreatic cell lineages and may also be required for motor neuron generation. Mutations in this gene have been associated with maturity-onset diabetes of the young. [provided by RefSeq, Jul 2008]

ID gène: 3670

UniProt: P61371

Pathways: Positive Regulation of Peptide Hormone Secretion, Intracellular Steroid Hormone Receptor Signaling Pathway, Peptide Hormone Metabolism, Regulation of Intracellular Steroid Hormone Receptor Signaling, Nuclear Hormone Receptor Binding, Chromatin Binding