CD59 anticorps
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- Antigène Voir toutes CD59 Anticorps
- CD59
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Reactivité
- Humain
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Hôte
- Souris
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Clonalité
- Monoclonal
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Conjugué
- Cet anticorp CD59 est non-conjugé
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Application
- Flow Cytometry (FACS), Western Blotting (WB), Immunoprecipitation (IP), Blocking Antibody (Inhibition)
- Stérilité
- 0.2 μm filtered
- niveau d'endotoxine
- Low endotoxin level
- Clone
- MEM-43
- Top Product
- Discover our top product CD59 Anticorps primaire
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- Indications d'application
- For flow cytometry and Western blotting dilutions to be used depend on detection system applied. It is recommended that users test the reagent and determine their own optimal dilutions. The typical starting working dilution is 1:10. For neutralization of biological activity dilutions have to be made according to the amounts endotoxin to be inactivated.
- Restrictions
- For Research Use only
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- Buffer
- PBS and 0.1 % bovine serum albumin with low endotoxin level.
- Stock
- 4 °C
- Stockage commentaire
- Product should be stored at 4 °C. Under recommended storage conditions, product is stable for one year.
- Date de péremption
- 12 months
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Lipopolysaccharide signal transduction in oral keratinocytes--involvement of CD59 but not CD14." dans: Cellular signalling, Vol. 15, Issue 9, pp. 861-9, (2003) (PubMed).
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Lipopolysaccharide signal transduction in oral keratinocytes--involvement of CD59 but not CD14." dans: Cellular signalling, Vol. 15, Issue 9, pp. 861-9, (2003) (PubMed).
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- Antigène
- CD59
- Autre désignation
- CD59 (CD59 Produits)
- Synonymes
- anticorps 16.3A5, anticorps 1F5, anticorps EJ16, anticorps EJ30, anticorps EL32, anticorps G344, anticorps HRF-20, anticorps HRF20, anticorps MAC-IP, anticorps MACIF, anticorps MEM43, anticorps MIC11, anticorps MIN1, anticorps MIN2, anticorps MIN3, anticorps MIRL, anticorps MSK21, anticorps p18-20, anticorps Cd59a, anticorps Cd59b, anticorps MACIP, anticorps CD59 molecule (CD59 blood group), anticorps CD59 molecule, anticorps CD59, anticorps Cd59
- Sujet
- The antibody is the prototypic antibody for the CD59 determinant, a PI-linked glycoprotein of 18-25 kDa, which is broadly expressed on most types of cells. The antigen is the major complement-protecting molecule of human cells. It is expressed on all leukocytes, erythrocytes and most other cell types. Binding of this antibody inhibits the complement-protecting activity of CD59. CD59 is one of the complement regulatory membrane proteins that is missing in Paroxysmal Nocturnal Haemoglobinuria (PNH). Anti CD59 reagents may be useful in the differential diagnosis of PNH type II and PNH type I. Recently a role for CD59 in LPS signal transduction has been reported in keratinocytes. The antibody reacts with well defined epitope (W40, R-53) on CD59 Molecule.
- Pathways
- Système du Complément
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