ERBB3 anticorps

N° du produit ABIN232941

Cet anticorps anti-ERBB3 Monoclonal Souris (Clone H3-90-6) (ABIN232941) détecte spécifiquement ERBB3 dans IF, FACS et IP. L’anticorps est réactif avec des échantillons de Humain.

Aperçu rapide pour ERBB3 anticorps (ABIN232941)

Antigène: ERBB3 (Receptor Tyrosine-Protein Kinase ErbB-3 (ERBB3))

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp ERBB3 est non-conjugé

Application: Immunofluorescence (IF), Flow Cytometry (FACS), Immunoprecipitation (IP)

Clone: H3-90-6

Détail du produit anti-ERBB3 anticorps

Specificité: Does not block the binding of heregulin to c-erbB-31, has no effect on tyrosine kinase activity1, receptor internalization1, or tumorigenic growth of cells overexpressing the cerbB- 32. It is particularly well suited for immunoprecipitation of unoccupied as well as the occupied receptor1. Species cross-reactivity: human.

Purification: Protein A purified

Immunogène: Extracellular fragment of recombinant human c-erbB-3/HER-3 oncoprotein.

Isotype: IgG2a

Information d'application

Indications d'application: Approved: Flo, IF, IP

Usage: Suitable for use in Flow Cytometry, Immunofluorescence, Immunoprecipitation, Effect on Heregulin (NDF) Binding (Non-inhibitory) and Effect on Tumor Growth (Non-inhibitory). Not suitable for Western Blot. Immunoprecipitation: 2 μg/mg protein lysate. Use Protein A. Well suited for Immunoprecipitation of unoccupied as well as occupied receptor. Positive control: T47D cells. The applications listed have been tested for the unmodified form of this product. Other forms have not been tested.

Not recommended for: IHC-P, WB

Commentaires:

Target Species of Antibody: Human

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: PBS,  pH 7.4.

Agent conservateur: Azide free

Stock: 4 °C,-20 °C

Stockage commentaire: Short term: 4°C
Long term: Add glycerol (40-50%) -20°C.

Détails sur ERBB3

Antigène: ERBB3 (Receptor Tyrosine-Protein Kinase ErbB-3 (ERBB3))

Autre désignation: HER3 / ERBB3

Sujet: Name/Gene ID: ERBB3
Subfamily: EGF Receptor
Family: Protein Kinase

Synonyms: ERBB3, C-erbB-3, C-erbB3, ErbB-3, HER3, p85-sErbB3, p45-sErbB3, MDA-BF-1, ErbB3-S, LCCS2, p180-ErbB3

ID gène: 2065

UniProt: P21860

Pathways: Signalisation RTK, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway