SNCA anticorps

N° du produit ABIN236423

L’anticorps Souris Monoclonal anti-SNCA a été validé pour WB, ELISA, IHC (p) et IHC (f). Il convient pour détecter SNCA dans des échantillons de Humain.

Aperçu rapide pour SNCA anticorps (ABIN236423)

Antigène: SNCA (Synuclein, alpha (SNCA))

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp SNCA est non-conjugé

Application: Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Formalin-fixed Sections) (IHC (f))

Clone: 4D6

Détail du produit anti-SNCA anticorps

Specificité: Reacts well with alpha-synuclein in Western blots and frozen and formalin-fixed/paraffin-embedded tissue sections. Recognizes human alpha-synuclein. Synuclein-alpha is the major component of Lewy bodies and Lewy neuritis in sporadic PD. dementia with Lewy Bodies and Lewy Body variant of AD. Lewy bodies are composed of truncated and phosphorylated intermediate neurofilament proteins, alpha synuclein, ubiquitin and associated enzymes. The synuclein phosphoproteins (15-20 kDa) are small highly conserved proteins in vertebrates. The synuclein family includes alpha and beta synucleins and loosely related gamma-synuclein and synoretin. The expression is abundant in neurons and typically localized at presynaptic terminals.

Attributs du produit: MAb to Synuclein Alpha, Monoclonal antibody to Human Synuclein alpha, Tissue culture supernatant

Purification: Protein A column Chromatography. Cell culture

Immunogène: Purified E. coli produced human alpha-synuclein

Isotype: IgG1

Information d'application

Indications d'application: Western/Dot blot (1:100 - 1:10.000) ELISA Immunohistochemistry: (1:100 - 1:1.000) frozen and formalin-fixed paraffin-embedded tissues (No formic acid, enzyme or HIER required). Each laboratory should determine an optimum working titer for use in its particular application. Other applications have not been tested but use in such assays should not necessarily be excluded.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: PBS.

Agent conservateur: Without preservative

Conseil sur la manipulation: Avoid multiple freeze/thaw cycles.
Centrifuge product if not completely clear after standing at room temperature.
Prepare working dilution only prior to immediate use.

Stock: -20 °C

Stockage commentaire: Store at -20 °C.

Détails sur SNCA

Antigène: SNCA (Synuclein, alpha (SNCA))

Autre désignation: Synuclein alpha

Pathways: Synaptic Membrane, Regulation of G-Protein Coupled Receptor Protein Signaling, Positive Regulation of Endopeptidase Activity, Regulation of Carbohydrate Metabolic Process, Platelet-derived growth Factor Receptor Signaling, Negative Regulation of Transporter Activity, Regulation of long-term Neuronal Synaptic Plasticity