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GDF15 anticorps (N-Term)

GDF15 Reactivité: Humain FACS, cELISA Hôte: Souris Monoclonal ME-6D10 unconjugated
N° du produit ABIN238331
  • Antigène Voir toutes GDF15 Anticorps
    GDF15 (Growth Differentiation Factor 15 (GDF15))
    Épitope
    • 16
    • 15
    • 11
    • 8
    • 7
    • 5
    • 5
    • 5
    • 3
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 30-194, N-Term
    Reactivité
    • 85
    • 29
    • 23
    • 1
    • 1
    Humain
    Hôte
    • 84
    • 10
    • 2
    • 1
    Souris
    Clonalité
    • 85
    • 11
    • 1
    Monoclonal
    Conjugué
    • 48
    • 15
    • 9
    • 8
    • 3
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp GDF15 est non-conjugé
    Application
    • 83
    • 52
    • 36
    • 15
    • 13
    • 13
    • 7
    • 7
    • 6
    • 5
    • 3
    • 3
    • 2
    • 1
    Flow Cytometry (FACS), Cell-ELISA (cELISA)
    Purification
    Protein G
    Immunogène
    genetic immunisation with cDNA encoding aa30-194 (N-term) of MIC-1 proprotein
    Clone
    ME-6D10
    Isotype
    IgG1
    Top Product
    Discover our top product GDF15 Anticorps primaire
  • Indications d'application
    Flow cytometry: 1.2 µg/10^6 cells
    CELISA: 1:200 - 1:400
    For each application a titration should be performed to determine the optimal concentration.
    Commentaires

    Synonyms: GDF15

    Restrictions
    For Research Use only
  • Buffer
    PBS, pH 7.2
    Conseil sur la manipulation
    Avoid repeated freezing and thawing.
    Stock
    4 °C
    Stockage commentaire
    short term: 2 °C - 8 °C, long term: -20 °C
  • Antigène
    GDF15 (Growth Differentiation Factor 15 (GDF15))
    Autre désignation
    MIC-1 (GDF15 Produits)
    Synonymes
    anticorps GDF15, anticorps GDF-15, anticorps MIC-1, anticorps MIC1, anticorps NAG-1, anticorps PDF, anticorps PLAB, anticorps PTGFB, anticorps SBF, anticorps growth differentiation factor 15, anticorps GDF15, anticorps Gdf15
    Sujet
    Macrophage inhibitory cytokine-1 (MIC-1) is a member of the transforming growth factor-ß superfamily that regulates a wide variety of physiological processes involved in tissue differentiation and maintenance. MIC-1 is synthesized as a 62-kDa intracellular protein, which, after cleavage by a furin like protease, is secreted as a 25-kDa disulphide-linked dimeric protein. Expression of MIC-1 results in inhibition of macrophage activation, regulated by the p53 pathway, in response to pro-inflammatory monokines. MIC-1 is involved in tumour pathogenesis and its measurement can be used as a clinical tool for the diagnosis of a wide range of cancers. It could be a useful marker for aggressive prostate cancer while MIC-1 is upregulated in advanced and more aggressive prostatic tumours.
    UniProt
    Q99988
    Pathways
    SARS-CoV-2 Protein Interactome
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