CD4 anticorps

N° du produit ABIN238364

L’anticorps Souris Monoclonal anti-CD4 a été validé pour FACS, WB, IHC (fro), Func et EIA. Il convient pour détecter CD4 dans des échantillons de Humain.

Aperçu rapide pour CD4 anticorps (ABIN238364)

Antigène: CD4

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp CD4 est non-conjugé

Application: Flow Cytometry (FACS), Western Blotting (WB), Immunohistochemistry (Frozen Sections) (IHC (fro)), Functional Studies (Func), Enzyme Immunoassay (EIA)

Clone: 13B8-2

Détail du produit anti-CD4 anticorps

Specificité: The CD4 antigen is a monomeric transmembrane glycoprotein with a molecular weight (Mr) of 60 kDa. CD4 Molecule is expressed on a specific subset of peripheral blood T lymphocytes named ''helper/inducer''. The CD4 antige is present on approximately 45 % of peripheral blood lymphocytes (T4 lymphocytes), 80 % of thymocytes and with a lower density of 100 % of monocytes and on some neutrophils.

Attributs du produit: Synonyms: T4/Leu-3, T-cell surface glycoprotein CD4, T-cell surface antigen T4/Leu-3

Immunogène: Human thymocytes

Isotype: IgG1

Information d'application

Indications d'application: Flow cytometry: Studies of CD4 expressing cells. Fluorescence microscopy or Flow cytometry: 2 g/5x10e5 cells/test. Immunohistochemistry: Working dilution 1/25-1/50. Only suitable on cryostat sections or cell smears.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Stockage

Reconstitution: Reconstitute with 1 mL distilled water.

Concentration: 0.2 mg/mL (prior to lyophilization)

Buffer: PBS containing 1 mg/mL BSA as stabilizer without preservatives.

Agent conservateur: Without preservative

Stock: 4 °C/-20 °C

Stockage commentaire: Store lyophilized (preferably in a desiccator) at 2-8 °C and reconstituted (in aliquots) at-20 °C. Avoid repeated freezing and thawing.
Shelf life: one year from despatch.

Date de péremption: 12 months

Détails sur CD4

Antigène: CD4

Autre désignation: CD4

Sujet: CD4 is a single chain transmembraneous glycoprotein (59 kDa) which belongs to the immunoglobulin superfamily. CD4 is present on a subset of T lymphocytes ("helper/inducer" T cells) and is also expressed at a lower level on monocytes, tissue macrophages and granulocytes. The antigen is involved in binding to MHC class II molecules. The intracellular domain of the antigen is associated with p56lck protein tyrosine kinase.Synonyms: T-cell surface antigen T4/Leu-3, T-cell surface glycoprotein CD4

ID gène: 920

UniProt: P01730

Pathways: TCR Signaling, Maintenance of Protein Location, CXCR4-mediated Signaling Events