Transferrin Receptor anticorps (Biotin)

N° du produit ABIN238475

L’anticorps anti-Transferrin Receptor Monoclonal Souris est utilisé pour la détection de Transferrin Receptor dans des échantillons de Humain. Il a été validé pour FACS.

Aperçu rapide pour Transferrin Receptor anticorps (Biotin) (ABIN238475)

Antigène: Transferrin Receptor (TFRC) (Transferrin Receptor (p90, CD71) (TFRC))

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp Transferrin Receptor est conjugé à/à la Biotin

Application: Flow Cytometry (FACS)

Clone: MEM-75

Détail du produit anti-Transferrin Receptor anticorps (Biotin)

Immunogène: NALM-6 human pre-B cell line

Isotype: IgG1

Information d'application

Indications d'application: This biotinylated antibody is suitable for indirect Immunofluorescence analysis by Flow Cytometry. Suggested working dilution is 1:200.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Stockage

Concentration: 1.0 mg/mL

Buffer: PBS, pH ~7.4 containing 15 mM Sodium Azide as preservative

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C/-20 °C

Stockage commentaire: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer. Avoid repeated freezing and thawing.
Shelf Life: one year from despatch.

Date de péremption: 12 months

Détails sur Transferrin Receptor

Antigène: Transferrin Receptor (TFRC) (Transferrin Receptor (p90, CD71) (TFRC))

Autre désignation: CD71 / TFRC

Sujet: CD71 (transferrin receptor) is a type II transmembrane glycoprotein expressed as homodimer in erythroid blood cell line and in activated leukocytes. Upon binding of holotransferrin (complex of transferrin and iron ions), CD71 is internalized by clathrin-mediated endocytosis. Acidification of endosomes by vesicular membrane proton pumps leads to dissociation of iron ions, whereas transferrin (apotransferrin) remains associated with CD71 and recycles to the cell surface, where it is released upon exposure to normal pH . CD71 is also involved in uptake of non-transferrin bound iron.Synonyms: TfR1, Transferrin receptor protein 1, p90

UniProt: P02786

Pathways: Transition Metal Ion Homeostasis