FZD1 anticorps
Aperçu rapide pour FZD1 anticorps (ABIN2431911)
Antigène
Voir toutes FZD1 (Fzd1) AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Purification
- Antigen affinity purification
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Immunogène
- Synthetic peptide of human FZD1
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Isotype
- IgG
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Indications d'application
- Optimal working dilution should be determined by the investigator.
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Restrictions
- For Research Use only
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Format
- Liquid
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Conseil sur la manipulation
- Avoid freeze / thaw cycles.
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Stock
- -20 °C/-80 °C
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Stockage commentaire
- Store at -20°C (regular) and -80°C (long term).
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- FZD1 (Fzd1) (Frizzled Family Receptor 1 (Fzd1))
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Autre désignation
- FZD1
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Sujet
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Members of the 'frizzled' gene family encode 7-transmembrane domain proteins that are receptors for Wnt signaling proteins. The FZD1 protein contains a signal peptide, a cysteine-rich domain in the N-terminal extracellular region, 7 transmembrane domains, and a C-terminal PDZ domain-binding motif. The FZD1 transcript is expressed in various tissues. May be involved in transduction and intercellular transmission of polarity information during tissue morphogenesis and/or in differentiated tissues. Activated by Wnt3A, Wnt3, Wnt1 and to a lesser extent Wnt2, but not by Wnt4, Wnt5A, Wnt5B, Wnt6, Wnt7A or Wnt7B.
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Poids moléculaire
- Calculated MW: 71 kDa
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Pathways
- Signalisation WNT, Asymmetric Protein Localization
Antigène
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