NUP153 anticorps (AA 610-1191)

N° du produit ABIN2452062

Cité dans 2 publications. Cet anticorps anti-NUP153 Monoclonal Rat (Clone R4C8) (ABIN2452062) détecte spécifiquement NUP153 dans WB, ELISA, IF et ICC. L’anticorps est réactif avec des échantillons de Rat.

Aperçu rapide pour NUP153 anticorps (AA 610-1191) (ABIN2452062)

Antigène: NUP153 (Nucleoporin 153kDa (NUP153))

Reactivité: Rat

Hôte: Rat

Clonalité: Monoclonal

Conjugué: Cet anticorp NUP153 est non-conjugé

Application: Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunocytochemistry (ICC)

Clone: R4C8

Détail du produit anti-NUP153 anticorps

Épitope: AA 610-1191

Specificité: Specific to human, mouse, rat and monkey Nup153 proteins.

Réactivité croisée (Details): Not tested for other species

Attributs du produit: When injected into the nucleus,R4C8 accumulates into the nuclear pores of Hela cells. R4C8 works in immuno-cytochemistry very well.

Purification: Purified

Stérilité: Sterile filtered

Immunogène: Recombinant GST-fused rat Nup153 (610-1191aa, Zn finger and FG repeats domain)

Isotype: IgG2a kappa

Information d'application

Indications d'application: 1. Western blotting: 160 kDa single band in Hela cell extract
2. Immunocytochemistry
3. ELISA
Other applications have not been tested.

Additional comments:
When injected into the nucleus, R4C8 accumulates into the nuclear pores of Hela cells.
R4C8 works in immuno-cytochemistry very well.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS, 50 % glycerol

Agent conservateur: Azide free

Stock: -20 °C

Stockage commentaire: Upon receipt aliquot and store at -20 C

Références pour anticorps anti-NUP153 (ABIN2452062)

Lim, Fahrenkrog, Köser, Schwarz-Herion, Deng, Aebi: "Nanomechanical basis of selective gating by the nuclear pore complex." dans: Science (New York, N.Y.), Vol. 318, Issue 5850, pp. 640-3, (2007) (PubMed).

Ullman, Shah, Powers, Forbes: "The nucleoporin nup153 plays a critical role in multiple types of nuclear export." dans: Molecular biology of the cell, Vol. 10, Issue 3, pp. 649-64, (1999) (PubMed).

Détails sur NUP153

Antigène: NUP153 (Nucleoporin 153kDa (NUP153))

Autre désignation: Nup153

Sujet: The nuclear pore complex (NPC) regulates cargo transport between the cytoplasm and the nucleus. Nup (Nucleoporin) 153 is a large (153 kDa) O-linked glycoprotein which is a component of the basket structure located on the nucleoplasmic face of NPC. Nup153 plays a critical role in nuclear export of RNA and proteins. The antibody was purified from the serum-free cultured medium of the hybridoma under mild conditions by propriety chromatography processes.

UniProt: P49790

Pathways: Protein targeting to Nucleus