NUP98 anticorps (AA 1-466)

N° du produit ABIN2452066

Cet anticorps Rat Monoclonal détecte spécifiquement NUP98 dans WB, ELISA, IF, ICC et DB. Il présente une réactivité avec des échantillons de Humain, Souris, Rat, Saccharomyces cerevisiae et Schizosaccharomyces pombe. Il a été cité dans 2+ publications.

Aperçu rapide pour NUP98 anticorps (AA 1-466) (ABIN2452066)

Antigène: NUP98 (Nucleoporin 98kDa (NUP98))

Reactivité: Humain, Souris, Rat, Saccharomyces cerevisiae, Schizosaccharomyces pombe

Hôte: Rat

Clonalité: Monoclonal

Conjugué: Cet anticorp NUP98 est non-conjugé

Application: Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunocytochemistry (ICC), Dot Blot (DB)

Clone: 2H10

Détail du produit anti-NUP98 anticorps

Épitope: AA 1-466

Réactivité croisée (Details): This antibody does not react with Tetrahymena.
Other species have not been tested.

Purification: Purified

Stérilité: Sterile filtered

Immunogène: Recombinant GST-fused human Nup98 (aa 1-466)

Isotype: IgG2c kappa

Information d'application

Indications d'application: 1) Western blotting
2) Immunocytochemistry
3) ELISA
4) Dot blotting

Properties:
When injected into the cytoplasm, this antibody accumulates into the nuclear pores of HeLa cells and inhibits nuclear localization of endogenous Ran.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS, 50 % glycerol. Azide- and carrier protein-free.

Agent conservateur: Azide free

Stock: -20 °C

Stockage commentaire: Upon arrival centrifuge briefly and store at -20 C.

Références pour anticorps anti-NUP98 (ABIN2452066)

Iwamoto, Asakawa, Ohtsuki, Osakada, Koujin, Hiraoka, Haraguchi: "Monoclonal antibodies recognize gly-leu-phe-gly repeat of nucleoporin nup98 of tetrahymena, yeasts, and humans." dans: Monoclonal antibodies in immunodiagnosis and immunotherapy, Vol. 32, Issue 2, pp. 81-90, (2013) (PubMed).

Fukuhara, Ozaki, Shikata, Katahira, Yoneda, Ogino, Tachibana: "Specific monoclonal antibody against the nuclear pore complex protein, nup98." dans: Hybridoma (2005), Vol. 24, Issue 5, pp. 244-7, (2005) (PubMed).

Détails sur NUP98

Antigène: NUP98 (Nucleoporin 98kDa (NUP98))

Autre désignation: Nup98

Sujet: Nucleoporin 98 (Nup98) is a component of nuclear pore complex (NPC), which is a large protein assembly embedded in the nuclear envelope. It is localized on both nuclear and cytoplasmic side of NPC. This protein contains glycine-leucine-phenylalanine-glycine (GLFG) amino acid repeats and plays a critical role in nuclear trafficking. Nup98 plays a specific role in the RNA export. Nup98 gene is fused to a variety of partner genes in human myeloid and T-cell malignancies via chromosomal translocation. This hybridoma has been established by Prof. T. Tachibana's Lab. at Osaka City Univ.

UniProt: Q9HDC8

Pathways: Stem Cell Maintenance, Protein targeting to Nucleus, SARS-CoV-2 Protein Interactome